Keyphrases
Cell Survival
100%
Motor Impairment
100%
Lysosomal Function
100%
Cell Delay
100%
Niemann-Pick Type
100%
Apolipoprotein D
100%
Oxidative Stress
13%
Lysosome
13%
Sphingomyelin
13%
Lysosomal Storage Disease
13%
Functional Integrity
13%
Purkinje Neuron
13%
Lysosomal Membrane Permeabilization
13%
Cell Viability
6%
Age-matched
6%
Control Subjects
6%
Fibroblasts
6%
Beneficial Effects
6%
Multivariable
6%
Neuronal Cells
6%
Gain-of-function mutation
6%
Neurodegeneration
6%
Early Onset
6%
Oxidative Damage
6%
Young Males
6%
Lipid Peroxidation
6%
Mouse Brain
6%
Young Female
6%
Functional Consequences
6%
Disease Pathology
6%
Or Injury
6%
Vulnerability
6%
Nervous System Diseases
6%
Motor Deficits
6%
Genetic Disease
6%
Cathepsin B
6%
Brain Section
6%
Cause of Disease
6%
Glia
6%
Glial Cells
6%
Acid Sphingomyelinase
6%
Galectin-3 (Gal-3)
6%
Primary Fibroblasts
6%
Patient Matched
6%
Cultured Fibroblasts
6%
Patient Cells
6%
Lipid Peroxides
6%
Disease Model Mice
6%
Lysosomal Acidification
6%
Function Maintenance
6%
Lysosomal Targeting
6%
Lipid-binding Protein
6%
Lysosomal Integrity
6%
Neuroscience
Stereotypic Movement Disorder
100%
Cell Survival
100%
Apolipoprotein D
100%
Fibroblast
23%
Oxidative Stress
15%
Sphingomyelin
15%
Lysosome
15%
Neurodegeneration
7%
Glia
7%
Cell Viability
7%
Loss of Function Mutation
7%
Sphingomyelin Phosphodiesterase
7%
Cathepsin B
7%
Lipid Peroxidation
7%
Nervous System Dysfunction
7%
Galectin 3
7%
Lipid Peroxide
7%
Lipid Binding Protein
7%
Biochemistry, Genetics and Molecular Biology
Cell Survival
100%
Apolipoprotein D
100%
Fibroblast
23%
Oxidative Stress
15%
Lysosome
15%
Lysosomal Storage Disease
15%
Sphingomyelin
15%
Cell Viability
7%
Mouse Model
7%
Loss of Function Mutation
7%
Genetic Disorder
7%
Acid Sphingomyelinase
7%
Sphingomyelin Phosphodiesterase
7%
Cathepsin B
7%
Lipid Peroxidation
7%
Lipid Binding Protein
7%
Lipid Peroxide
7%
Galectin-3
7%
Alkalinization
7%