TY - JOUR
T1 - Anxiety Disorders in Adults with Autism Spectrum Disorder
T2 - A Population-Based Study
AU - Nimmo-Smith, Victoria
AU - Heuvelman, Hein
AU - Dalman, Christina
AU - Lundberg, Michael
AU - Idring, Selma
AU - Carpenter, Peter
AU - Magnusson, Cecilia
AU - Rai, Dheeraj
N1 - Funding Information:
This research was funded by Grant 3747-6849 from The Baily Thomas Charitable Foundation and by Grant 2017-010006 from the Swedish Research Council for Health, Working Life, and Welfare. This study was also supported by the National Institute for Health Research Biomedical Research Centre at the University Hospitals Bristol National Health Service Foundation Trust and the University of Bristol (Grant No. BRC-1215-2011) and Victoria Nimmo-Smith was funded by a National Institute for Health Research Academic Clinical Fellowship award (reference number ACF-2016-25-503).
Funding Information:
This research was funded by Grant 3747-6849 from The Baily Thomas Charitable Foundation and by Grant 2017-010006 from the Swedish Research Council for Health, Working Life, and Welfare. This study was also supported by the National Institute for Health Research Biomedical Research Centre at the University Hospitals Bristol National Health Service Foundation Trust and the University of Bristol (Grant No. BRC-1215-2011) and Victoria Nimmo-Smith was funded by a National Institute for Health Research Academic Clinical Fellowship award (reference number ACF-2016-25-503).
Publisher Copyright:
© 2019, The Author(s).
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Anxiety is common in children with ASD; however, the burden of specific anxiety disorders for adults with ASD is under-researched. Using the Stockholm Youth Cohort, we compared anxiety disorder diagnoses among autistic adults (n = 4049), with or without intellectual disability, and population controls (n = 217,645). We conducted additional sibling analyses. Anxiety disorders were diagnosed in 20.1% of adults with ASD compared with 8.7% of controls (RR = 2.62 [95% CI 2.47–2.79]), with greatest risk for autistic people without intellectual disability. Rates of almost all individual anxiety disorders were raised, notably obsessive–compulsive disorder and phobic anxiety disorders. Anxiety disorders were more common in full siblings and half-siblings of people with ASD. The implications of this are explored.
AB - Anxiety is common in children with ASD; however, the burden of specific anxiety disorders for adults with ASD is under-researched. Using the Stockholm Youth Cohort, we compared anxiety disorder diagnoses among autistic adults (n = 4049), with or without intellectual disability, and population controls (n = 217,645). We conducted additional sibling analyses. Anxiety disorders were diagnosed in 20.1% of adults with ASD compared with 8.7% of controls (RR = 2.62 [95% CI 2.47–2.79]), with greatest risk for autistic people without intellectual disability. Rates of almost all individual anxiety disorders were raised, notably obsessive–compulsive disorder and phobic anxiety disorders. Anxiety disorders were more common in full siblings and half-siblings of people with ASD. The implications of this are explored.
KW - Anxiety
KW - Autism spectrum disorder
KW - Epidemiology
KW - Intellectual disability
KW - Mental health
UR - http://www.scopus.com/inward/record.url?scp=85074011299&partnerID=8YFLogxK
U2 - 10.1007/s10803-019-04234-3
DO - 10.1007/s10803-019-04234-3
M3 - Article
C2 - 31621020
AN - SCOPUS:85074011299
SN - 0162-3257
VL - 50
SP - 308
EP - 318
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
IS - 1
ER -