TY - JOUR
T1 - Antidepressants during pregnancy
T2 - Guideline adherence and current practice amongst Dutch gynaecologists and midwives
AU - Molenaar, Nina M.
AU - Brouwer, Marlies E.
AU - Duvekot, Johannes J.
AU - Burger, Huibert
AU - Knijff, Esther M.
AU - Hoogendijk, Witte J.
AU - Bockting, Claudi L.H.
AU - de Wolf, G. S.
AU - Lambregtse-van den Berg, Mijke P.
N1 - Publisher Copyright:
© 2018 Elsevier Ltd
PY - 2018/6
Y1 - 2018/6
N2 - Background and objectives: prescription rates of antidepressants during pregnancy range from 2–3% in The Netherlands to 6.2% in the USA. Inconclusive evidence about harms and benefits of antidepressants during pregnancy leads to variation in advice given by gynaecologists and midwives. The objective was to investigate familiarity with, and adherence to the Dutch multidisciplinary guideline on Selective Serotonin Reuptake Inhibitor (SSRI) use during pregnancy by gynaecologists and midwives in the Netherlands. Methods: an online survey was developed and send to Dutch gynaecologists and midwives. The survey consisted mainly of multiple-choice questions addressing guideline familiarity and current practice of the respondent. Also, caregiver characteristics associated with guideline adherence were investigated. Findings: a total of 178 gynaecologists and 139 midwives responded. Overall familiarity with the Dutch guideline was 92.7%. However, current practice and advice given to patients by caregivers differed substantially, both between gynaecologists and midwives as well as within both professions. Overall guideline adherence was 13.9%. Multivariable logistic regression showed that solely caregiver profession was associated with guideline adherence, with gynaecologists having a higher adherence rate (OR 2.10, 95%CI 1.02–4.33) than midwives. Key conclusion: although reported familiarity with the guideline is high, adherence to the guideline is low, possibly resulting in advice to patients that is inconsistent with guidelines and unwanted variation in current practice. Implications for practice: further implementation of the recommendations as given in the guideline should be stimulated. Additional research is needed to examine how gynaecologists and midwives can be facilitated to follow the recommendations of the clinical guideline on SSRI use during pregnancy.
AB - Background and objectives: prescription rates of antidepressants during pregnancy range from 2–3% in The Netherlands to 6.2% in the USA. Inconclusive evidence about harms and benefits of antidepressants during pregnancy leads to variation in advice given by gynaecologists and midwives. The objective was to investigate familiarity with, and adherence to the Dutch multidisciplinary guideline on Selective Serotonin Reuptake Inhibitor (SSRI) use during pregnancy by gynaecologists and midwives in the Netherlands. Methods: an online survey was developed and send to Dutch gynaecologists and midwives. The survey consisted mainly of multiple-choice questions addressing guideline familiarity and current practice of the respondent. Also, caregiver characteristics associated with guideline adherence were investigated. Findings: a total of 178 gynaecologists and 139 midwives responded. Overall familiarity with the Dutch guideline was 92.7%. However, current practice and advice given to patients by caregivers differed substantially, both between gynaecologists and midwives as well as within both professions. Overall guideline adherence was 13.9%. Multivariable logistic regression showed that solely caregiver profession was associated with guideline adherence, with gynaecologists having a higher adherence rate (OR 2.10, 95%CI 1.02–4.33) than midwives. Key conclusion: although reported familiarity with the guideline is high, adherence to the guideline is low, possibly resulting in advice to patients that is inconsistent with guidelines and unwanted variation in current practice. Implications for practice: further implementation of the recommendations as given in the guideline should be stimulated. Additional research is needed to examine how gynaecologists and midwives can be facilitated to follow the recommendations of the clinical guideline on SSRI use during pregnancy.
KW - Antidepressive agents
KW - Depression
KW - Guideline adherence
KW - Medication therapy management
KW - Peripartum period
KW - Pregnancy
UR - http://www.scopus.com/inward/record.url?scp=85042928506&partnerID=8YFLogxK
U2 - 10.1016/j.midw.2018.02.018
DO - 10.1016/j.midw.2018.02.018
M3 - Article
C2 - 29524773
AN - SCOPUS:85042928506
SN - 0266-6138
VL - 61
SP - 29
EP - 35
JO - Midwifery
JF - Midwifery
ER -