Anticardiolipin Antibodies in Pregnant Patients with Systemic Lupus Erythematosus

Renato Lenzi, Jacob H. Rand, Harry Spiera, Michael D. Lockshin

Research output: Contribution to journalLetterpeer-review

27 Scopus citations


To the Editor: There has recently been an increase in recognition of the association between anticardiolipin antibodies and the “lupus anticoagulant” phenomenon (which these antibodies are believed to cause) and an increased risk of fetal morbidity and mortality. In an article in the July 18 issue,1 Lockshin et al. confirmed this association in pregnant patients with lupus. They also asserted that the anticardiolipin assay is a more sensitive test than the lupus-anticoagulant assay, since half their patients with anticardiolipin antibodies had no demonstrable lupus anticoagulant. In the course of our own investigations of anticardiolipin antibodies, we have found that the.

Original languageEnglish
Pages (from-to)1392-1393
Number of pages2
JournalNew England Journal of Medicine
Issue number21
StatePublished - 22 May 1986


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