Antibodies to nucleic acids in myasthenia gravis

M. Eric Gershwin; Wieslaw Glinski; Adam N. Bender; Steven P. Ringel; Alfred D. Steinberg; W. King Engel

doi:10.1159/000231597

Antibodies to nucleic acids in myasthenia gravis

M. Eric Gershwin, Wieslaw Glinski, Adam N. Bender, Steven P. Ringel, Alfred D. Steinberg, W. King Engel

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12 Scopus citations

Abstract

An increased frequency of antibodies to native DNA, thymocytes, and striated muscle was found in patients with myasthenia gravis (MG). The prevalence of such antibodies lends considerable support to the concept of MG as an autoimmune disorder and militates in favor of major abnormalities in the thymic dependent immune system. There was no correlation between scrum-blocking activity to acetylcholine receptor protein and antibodies to thymocytes.

Original language	English
Pages (from-to)	245-252
Number of pages	8
Journal	International Archives of Allergy and Immunology
Volume	51
Issue number	2
DOIs	https://doi.org/10.1159/000231597
State	Published - 1976
Externally published	Yes

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title = "Antibodies to nucleic acids in myasthenia gravis",

abstract = "An increased frequency of antibodies to native DNA, thymocytes, and striated muscle was found in patients with myasthenia gravis (MG). The prevalence of such antibodies lends considerable support to the concept of MG as an autoimmune disorder and militates in favor of major abnormalities in the thymic dependent immune system. There was no correlation between scrum-blocking activity to acetylcholine receptor protein and antibodies to thymocytes.",

author = "{Eric Gershwin}, M. and Wieslaw Glinski and Bender, {Adam N.} and Ringel, {Steven P.} and Steinberg, {Alfred D.} and {King Engel}, W.",

year = "1976",

doi = "10.1159/000231597",

language = "English",

volume = "51",

pages = "245--252",

journal = "International Archives of Allergy and Immunology",

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publisher = "S. Karger AG",

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T1 - Antibodies to nucleic acids in myasthenia gravis

AU - Eric Gershwin, M.

AU - Glinski, Wieslaw

AU - Bender, Adam N.

AU - Ringel, Steven P.

AU - Steinberg, Alfred D.

AU - King Engel, W.

PY - 1976

Y1 - 1976

N2 - An increased frequency of antibodies to native DNA, thymocytes, and striated muscle was found in patients with myasthenia gravis (MG). The prevalence of such antibodies lends considerable support to the concept of MG as an autoimmune disorder and militates in favor of major abnormalities in the thymic dependent immune system. There was no correlation between scrum-blocking activity to acetylcholine receptor protein and antibodies to thymocytes.

AB - An increased frequency of antibodies to native DNA, thymocytes, and striated muscle was found in patients with myasthenia gravis (MG). The prevalence of such antibodies lends considerable support to the concept of MG as an autoimmune disorder and militates in favor of major abnormalities in the thymic dependent immune system. There was no correlation between scrum-blocking activity to acetylcholine receptor protein and antibodies to thymocytes.

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U2 - 10.1159/000231597

DO - 10.1159/000231597

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AN - SCOPUS:0017078112

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EP - 252

JO - International Archives of Allergy and Immunology

JF - International Archives of Allergy and Immunology

SN - 1018-2438

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ER -

Antibodies to nucleic acids in myasthenia gravis

Abstract

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