Three antigen systems associated with the Epstein Barr virus were studied by immunofluorescence: membrane antigens (MA), intracellular 'early antigens' (EA), and intracellular viral capsid antigens (VCA). All Burkitt's lymphoma patients studied had antibodies to VCA and MA, and a majority also to EA. The patients had higher titers than control groups. High anti EA titers in patients brought into remissions indicate a bad prognosis as to recurrences. A decrease in antibodies to MA has been seen before late tumor recurrences. BCG inoculations temporarily increased the anti MA titers.
|Number of pages||5|
|State||Published - 1973|