Antibiotic Resistance in Municipal Wastewater: A Special Focus on Hospital Effluents

Charmaine Ng, Hongjie Chen, Ngoc Han Tran, Laurence Haller, Karina Yew Hoong Gin

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

4 Scopus citations

Abstract

Hospital effluents contain a hazardous amalgam of drug residues and infectious agents. Qualitative and quantitative evidence shows that hospital effluents are enriched in antibiotics, multidrug-resistant bacteria, antibiotic resistance genes and genetic vectors which could facilitate the horizontal transfer of these genes. This chapter provides an overview of the current status of antimicrobial resistance (AMR) surveillance in hospital effluents and draws comparisons to other AMR monitoring studies in domestic wastewaters and natural aquatic environments. We discuss approaches and standard tools that have been used to measure levels of AMR contamination and provide insights to the latest developments in the detection and profiling of AMR which have yet to gain traction in present surveillance programs.

Original languageEnglish
Title of host publicationHandbook of Environmental Chemistry
PublisherSpringer Science and Business Media Deutschland GmbH
Pages123-146
Number of pages24
DOIs
StatePublished - 2020
Externally publishedYes

Publication series

NameHandbook of Environmental Chemistry
Volume91
ISSN (Print)1867-979X

Keywords

  • Antibiotic residues
  • Antibiotic resistance genes
  • Antibiotic resistant bacteria
  • Hospital effluent
  • Resistome

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