Anti-glomerular basement membrane disease

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Anti-GBM antibody disease is a rare autoimmune disorder characterized by circulating autoantibodies directed against specific antigenic targets within the glomerular and alveolar basement membranes. It is extremely uncommon in children, and typically presents with acute renal failure caused by a rapidly progressive glomerulonephritis that is commonly associated with crescentic changes.

Original languageEnglish
Title of host publicationGlomerulonephritis
PublisherSpringer International Publishing
Number of pages8
ISBN (Electronic)9783319493794
ISBN (Print)9783319493787
StatePublished - 26 Feb 2019


  • ANCA: Antineutrophil cytoplasm antibodies
  • Alpha-3(IV) NC1: Alpha-3 chain of type IV collagen
  • ELISA: Enzyme-linked immunosorbent assay
  • HLA: Human leukocyte antigen


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