TY - JOUR
T1 - Anthropometric models to estimate fat mass at 3 days, 15 and 54 weeks
AU - Gopalakrishnamoorthy, Mahalakshmi
AU - Whyte, Kathryn
AU - Horowitz, Michelle
AU - Widen, Elizabeth
AU - Toro-Ramos, Tatiana
AU - Johnson, Jill
AU - Gidwani, Sonia
AU - Paley, Charles
AU - Rosenn, Barak
AU - Lin, Susan
AU - Thornton, John
AU - Pi-Sunyer, Xavier
AU - Gallagher, Dympna
N1 - Funding Information:
National Institutes of Health Grants T32-DK065522 (PI: S. Oberfield) supported Gopalakrishnamoorthy. U01-DK094463; U01-DK094463-Supplement (Supplement to promote diversity, -Ramos, PhD); P30-DK026687; T32-DK007559 (Toro-Ramos, Widen; Whyte); T32DK091227 (Widen); K99/R00HD086304 to Dr. Widen. Research reported in this publication was supported by the National Institutes of Health through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK, U01 DK094418, U01 DK094463, U01 DK094416, 5U01 DK094466 [RCU]), the National Heart, Lung, and Blood Institute (NHLBI, U01 HL114344, U01 HL114377), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD, U01 HD072834), the National Center for Complementary and Integrative Health (NCCIH), the NIH Office of Research on Women's Health (ORWH), the Office of Behavioral and Social Science Research (OBSSR), the NIH Office of Disease Prevention (ODP), the Indian Health Service, the Intramural Research Program of the NIDDK, and the Office of the Director, National Institutes of Health (OD). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. We thank the LIFE-Moms consortium members for their contributions to the development and oversight of the common measures and procedures shared across the trials.
Funding Information:
National Institutes of Health Grants T32‐DK065522 (PI: S. Oberfield) supported Gopalakrishnamoorthy. U01‐DK094463; U01‐DK094463‐Supplement (Supplement to promote diversity, ‐Ramos, PhD); P30‐DK026687; T32‐DK007559 (Toro‐Ramos, Widen; Whyte); T32DK091227 (Widen); K99/R00HD086304 to Dr. Widen. Research reported in this publication was supported by the National Institutes of Health through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK, U01 DK094418, U01 DK094463, U01 DK094416, 5U01 DK094466 [RCU]), the National Heart, Lung, and Blood Institute (NHLBI, U01 HL114344, U01 HL114377), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD, U01 HD072834), the National Center for Complementary and Integrative Health (NCCIH), the NIH Office of Research on Women's Health (ORWH), the Office of Behavioral and Social Science Research (OBSSR), the NIH Office of Disease Prevention (ODP), the Indian Health Service, the Intramural Research Program of the NIDDK, and the Office of the Director, National Institutes of Health (OD). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. We thank the LIFE‐Moms consortium members for their contributions to the development and oversight of the common measures and procedures shared across the trials. Funding information
Funding Information:
Office of the Director, National Institutes of Health; Indian Health Service,; NIH Office of Disease Prevention; Office of Behavioral and Social Science Research; NIH Office of Research on Women's Health; National Center for Complementary and Integrative Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development, Grant/Award Number: U01 HD072834; National Heart, Lung, and Blood Institute, Grant/Award Numbers: U01 HL114377, U01 HL114344; National Institute of Diabetes and Digestive and Kidney Diseases, Grant/Award Numbers: 5U01 DK094466, U01 DK094416, U01 DK094463, U01 DK094418; National Institutes of Health, Grant/Award Numbers: K99/R00HD086304, T32DK091227, T32‐DK007559, P30‐DK026687, U01‐DK094463, T32‐DK065522 Funding information
Publisher Copyright:
© 2021 World Obesity Federation
PY - 2022/3
Y1 - 2022/3
N2 - Background: Currently available infant body composition measurement methods are impractical for routine clinical use. The study developed anthropometric equations (AEs) to estimate fat mass (FM, kg) during the first year using air displacement plethysmography (PEA POD® Infant Body Composition System) and Infant quantitative magnetic resonance (Infant-QMR) as criterion methods. Methods: Multi-ethnic full-term infants (n = 191) were measured at 3 days, 15 and 54 weeks. Sex, race/ethnicity, gestational age, age (days), weight-kg (W), length-cm (L), head circumferences-cm (HC), skinfold thicknesses mm [triceps (TRI), thigh (THI), subscapular (SCP), and iliac (IL)], and FM by PEA POD® and Infant-QMR were collected. Stepwise linear regression determined the model that best predicted FM. Results: Weight, length, head circumference, and skinfolds of triceps, thigh, and subscapular, but not iliac, significantly predicted FM throughout infancy in both the Infant-QMR and PEA POD models. Sex had an interaction effect at 3 days and 15 weeks for both the models. The coefficient of determination [R2] and root mean square error were 0.87 (66 g) at 3 days, 0.92 (153 g) at 15 weeks, and 0.82 (278 g) at 54 weeks for the Infant-QMR models; 0.77 (80 g) at 3 days and 0.82 (195 g) at 15 weeks for the PEA POD models respectively. Conclusions: Both PEA POD and Infant-QMR derived models predict FM using skinfolds, weight, head circumference, and length with acceptable R2 and residual patterns.
AB - Background: Currently available infant body composition measurement methods are impractical for routine clinical use. The study developed anthropometric equations (AEs) to estimate fat mass (FM, kg) during the first year using air displacement plethysmography (PEA POD® Infant Body Composition System) and Infant quantitative magnetic resonance (Infant-QMR) as criterion methods. Methods: Multi-ethnic full-term infants (n = 191) were measured at 3 days, 15 and 54 weeks. Sex, race/ethnicity, gestational age, age (days), weight-kg (W), length-cm (L), head circumferences-cm (HC), skinfold thicknesses mm [triceps (TRI), thigh (THI), subscapular (SCP), and iliac (IL)], and FM by PEA POD® and Infant-QMR were collected. Stepwise linear regression determined the model that best predicted FM. Results: Weight, length, head circumference, and skinfolds of triceps, thigh, and subscapular, but not iliac, significantly predicted FM throughout infancy in both the Infant-QMR and PEA POD models. Sex had an interaction effect at 3 days and 15 weeks for both the models. The coefficient of determination [R2] and root mean square error were 0.87 (66 g) at 3 days, 0.92 (153 g) at 15 weeks, and 0.82 (278 g) at 54 weeks for the Infant-QMR models; 0.77 (80 g) at 3 days and 0.82 (195 g) at 15 weeks for the PEA POD models respectively. Conclusions: Both PEA POD and Infant-QMR derived models predict FM using skinfolds, weight, head circumference, and length with acceptable R2 and residual patterns.
KW - PEAPOD
KW - body composition
KW - infancy
KW - infant-QMR
KW - pediatrics
UR - http://www.scopus.com/inward/record.url?scp=85115617055&partnerID=8YFLogxK
U2 - 10.1111/ijpo.12855
DO - 10.1111/ijpo.12855
M3 - Article
C2 - 34558804
AN - SCOPUS:85115617055
VL - 17
JO - Pediatric obesity
JF - Pediatric obesity
SN - 2047-6302
IS - 3
M1 - e12855
ER -