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Antemortem Markers

  • Susan J. Van Rensburg
  • , Felix C.V. Potocnik
  • , Maritha J. Kotze
  • , Dan J. Stein

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

Alzheimer's disease is characterised by progressive difficulties in many areas of cognition and behavioural disturbance. The limited symptomatic treatments available currently are based on a detailed understanding of the neurochemical changes that in the brains of people with Alzheimer's disease and how they relate to specific symptoms. For example the mainstay of treatment, cholinesterase inhibitors, seeks to address presynaptic deficits in acetylcholine which underlie cognitive, attentional and behavioural aspects of the disorder.

Original languageEnglish
Title of host publicationPrinciples and Practice of Geriatric Psychiatry
Subtitle of host publicationThird Edition
PublisherJohn Wiley and Sons
Pages299-303
Number of pages5
ISBN (Print)9780470747230
DOIs
StatePublished - 2 Dec 2010
Externally publishedYes

Keywords

  • Acetylcholine
  • Behaviour
  • Cognition
  • Glutamate
  • Neurochemistry
  • Serotonin

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