Angiogenin Defines Heterogeneity at the Core of the Hematopoietic Niche

Marianna Di Scala; Andrés Hidalgo

doi:10.1016/j.stem.2016.08.017

Angiogenin Defines Heterogeneity at the Core of the Hematopoietic Niche

Marianna Di Scala
, Andrés Hidalgo

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

Successful hematopoietic regeneration demands preservation of stemness while enabling expansion and differentiation into blood lineages. Now, Silberstein et al. (2016) and Goncalves et al. (2016) identify a ribonuclease secreted by proximal niche cells that simultaneously drives quiescence of HSCs and proliferation of myeloid progenitors and dramatically enhances hematopoietic recovery after HSC transplantation.

Original language	English
Pages (from-to)	284-286
Number of pages	3
Journal	Cell Stem Cell
Volume	19
Issue number	3
DOIs	https://doi.org/10.1016/j.stem.2016.08.017
State	Published - 1 Sep 2016
Externally published	Yes

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title = "Angiogenin Defines Heterogeneity at the Core of the Hematopoietic Niche",

abstract = "Successful hematopoietic regeneration demands preservation of stemness while enabling expansion and differentiation into blood lineages. Now, Silberstein et al. (2016) and Goncalves et al. (2016) identify a ribonuclease secreted by proximal niche cells that simultaneously drives quiescence of HSCs and proliferation of myeloid progenitors and dramatically enhances hematopoietic recovery after HSC transplantation.",

author = "\{Di Scala\}, Marianna and Andr{\'e}s Hidalgo",

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year = "2016",

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AU - Di Scala, Marianna

AU - Hidalgo, Andrés

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N2 - Successful hematopoietic regeneration demands preservation of stemness while enabling expansion and differentiation into blood lineages. Now, Silberstein et al. (2016) and Goncalves et al. (2016) identify a ribonuclease secreted by proximal niche cells that simultaneously drives quiescence of HSCs and proliferation of myeloid progenitors and dramatically enhances hematopoietic recovery after HSC transplantation.

AB - Successful hematopoietic regeneration demands preservation of stemness while enabling expansion and differentiation into blood lineages. Now, Silberstein et al. (2016) and Goncalves et al. (2016) identify a ribonuclease secreted by proximal niche cells that simultaneously drives quiescence of HSCs and proliferation of myeloid progenitors and dramatically enhances hematopoietic recovery after HSC transplantation.

UR - https://www.scopus.com/pages/publications/84991096613

U2 - 10.1016/j.stem.2016.08.017

DO - 10.1016/j.stem.2016.08.017

M3 - Short survey

C2 - 27588743

AN - SCOPUS:84991096613

SN - 1934-5909

VL - 19

SP - 284

EP - 286

JO - Cell Stem Cell

JF - Cell Stem Cell

IS - 3

ER -

Angiogenin Defines Heterogeneity at the Core of the Hematopoietic Niche

Abstract

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