Anesthetic management of cerebral aneurysmectomy in a sickle cell anemia patient

I. Sampson, M. Pratila, V. Pratilas

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


The recognition of sickle cell disease is of great importance prior to anesthesia because it influences the management of the patient throughout the preoperative period. Abnormal hemoglobins leading to sickling occur most commonly in those of African origin and in this condition hypoxemia or acidosis precipitates sickling and both may occur during anesthesia. Sickling causes local stasis with hypoxia and acidosis with further sickling. The common sickling conditions are: -sickle cell disease (hemoglobin SS), sickle cell trait (hemoglobin AS) and sickle cell B thalasemia (hemoglobin SBT). Since sickling depends on the amount of hemoglobins in the blood, the first two conditions are those which constitute the greatest anesthetic risk. We present a patient who underwent surgery for an intracranial aneurysm. The modification of our usual anesthetic management of this condition in a patient with sickle cell disease is discussed.

Original languageEnglish
Pages (from-to)326-328
Number of pages3
JournalMount Sinai Journal of Medicine
Issue number4
StatePublished - 1982
Externally publishedYes


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