TY - JOUR
T1 - Analysis of the left atrial appendage morphology by intracardiac echocardiography in patients with atrial fibrillation
AU - Blendea, Dan
AU - Heist, E. Kevin
AU - Danik, Stephan B.
AU - Barrett, Conor
AU - Ruskin, Jeremy N.
AU - Mansour, Moussa
N1 - Funding Information:
This work was partially supported by the Deane Institute for Integrative Research in Atrial Fibrillation and Stroke D.Blendea.E.K.Heist.S.B.Danik.C.Barrett.J.N.Ruskin. M. Mansour (*) Cardiac Arrhythmia Service, Heart Center, Massachusetts General Hospital, GRB 109, 55 Fruit Street, Boston, MA 02114, USA e-mail: [email protected]
Funding Information:
Conflicts of interest Dr. Dan Blendea, Dr. Stephan Danik, and Dr. Conor Barrett have no potential conflicts of interest. Dr. E. Kevin Heist has served as a consultant and received research grants from St. Jude Medical and Boston Scientific. Dr. Jeremy N. Ruskin has served as consultant for Medtronic and Biosense Webster and received honorarium for faculty participation in Fellows program from Boston Scientific and St. Jude Medical. Dr. Moussa Mansour has served as a consultant for Biosense Webster.
PY - 2011/9
Y1 - 2011/9
N2 - Background Detailed information regarding the structure and dimensions of the left atrial appendage (LAA) is required to guide implantation of LAA occlusion devices in patients with atrial fibrillation (AF). Currently, this procedure is guided by transesophageal echocardiography (TEE). Objective The objective of this study was to evaluate the accuracy of intracardiac echocardiography (ICE) in assessing LAA dimensions. Methods The LAA anatomy was analyzed in 21 consecutive patients (age 62±9 years, five women, six paroxysmal AF) who underwent catheter ablation for AF. All patients had pre-procedural scans (computed tomography (CT), N=9; magnetic resonance imaging (MRI), N=12) of the left atrium (LA). An 8-Fr phased-array ICE catheter was used to obtain images of the LAA. The LAA was visualized with the ICE probe placed sequentially in the right atrium (RA, N=21 patients), in the coronary sinus (CS, N=20 patients), and in the LA (N=21 patients). Results ICE imaging from the LA showed a LAA ostium diameter of 24±4 mm and a LAA depth of 32±4 mm. There was strong correlation between the measurements by ICE and the values obtained by CT and MRI. The LAA was visualized in all cases from all locations (RA, CS, and LA), but complete visualization of the LAA could not be obtained from the RA and the CS in a significant number of cases, preventing accurate measurements. Conclusions Imaging of LAA using an ICE probe positioned in the LA results in accurate measurements of LAA dimensions. This imaging modality could potentially be used during implantation of LAA occlusion devices as an alternative to TEE.
AB - Background Detailed information regarding the structure and dimensions of the left atrial appendage (LAA) is required to guide implantation of LAA occlusion devices in patients with atrial fibrillation (AF). Currently, this procedure is guided by transesophageal echocardiography (TEE). Objective The objective of this study was to evaluate the accuracy of intracardiac echocardiography (ICE) in assessing LAA dimensions. Methods The LAA anatomy was analyzed in 21 consecutive patients (age 62±9 years, five women, six paroxysmal AF) who underwent catheter ablation for AF. All patients had pre-procedural scans (computed tomography (CT), N=9; magnetic resonance imaging (MRI), N=12) of the left atrium (LA). An 8-Fr phased-array ICE catheter was used to obtain images of the LAA. The LAA was visualized with the ICE probe placed sequentially in the right atrium (RA, N=21 patients), in the coronary sinus (CS, N=20 patients), and in the LA (N=21 patients). Results ICE imaging from the LA showed a LAA ostium diameter of 24±4 mm and a LAA depth of 32±4 mm. There was strong correlation between the measurements by ICE and the values obtained by CT and MRI. The LAA was visualized in all cases from all locations (RA, CS, and LA), but complete visualization of the LAA could not be obtained from the RA and the CS in a significant number of cases, preventing accurate measurements. Conclusions Imaging of LAA using an ICE probe positioned in the LA results in accurate measurements of LAA dimensions. This imaging modality could potentially be used during implantation of LAA occlusion devices as an alternative to TEE.
KW - Atrial fibrillation
KW - Intracardiac echocardiography
KW - Left atrial appendage
KW - Left atrial appendage geometry
KW - Left atrial appendage occlusion devices
UR - https://www.scopus.com/pages/publications/80053560840
U2 - 10.1007/s10840-011-9559-z
DO - 10.1007/s10840-011-9559-z
M3 - Article
C2 - 21455699
AN - SCOPUS:80053560840
SN - 1383-875X
VL - 31
SP - 191
EP - 196
JO - Journal of Interventional Cardiac Electrophysiology
JF - Journal of Interventional Cardiac Electrophysiology
IS - 3
ER -