An update on the management of hepatitis C virus and human immunodeficiency virus co-infection

Bryan Tolentino, Ritu R. Singh, Suresh Misra, Douglas T. Dieterich, Dost Sarpel

Research output: Contribution to journalReview articlepeer-review

Abstract

An estimated 2.3 million people globally are co-infected with HIV and HCV. Liver disease is now a leading cause of non-AIDS-related mortality among HIV-infected patients. The development of direct-acting antiviral agents has revolutionized the treatment of HIV/HCV co-infection with sustained virologic response response rates above 95% in most patient populations. This article provides an update on the management of acute and chronic HCV in patients co-infected with HIV including a section on drug-drug interactions.

Original languageEnglish
Pages (from-to)185-195
Number of pages11
JournalFuture Virology
Volume14
Issue number3
DOIs
StatePublished - 1 Mar 2019

Keywords

  • DAA
  • HCV
  • HIV
  • HIV-HCV interaction
  • acute HCV
  • chronic HCV
  • co-infection
  • direct-acting antivirals
  • drug interactions
  • interferon

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