An open-label study to evaluate the transition of patients with chronic plaque psoriasis from cyclosporine to alefacept.

Melissa A. Magliocco; Ann Marie Lozano; Claudia Van Saders; Kristine W. Schuler; Alice B. Gottlieb

An open-label study to evaluate the transition of patients with chronic plaque psoriasis from cyclosporine to alefacept.

Melissa A. Magliocco
, Ann Marie Lozano
, Claudia Van Saders
, Kristine W. Schuler
, Alice B. Gottlieb

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Eleven patients with well-controlled psoriasis on cyclosporine (Physician's Global Assessment [PGA] of "mild" or better) participated in an open-label study that evaluated a strategy for transition to alefacept. Using this transition strategy, 7 of 11 patients (64%) maintained PGA scores. Quality of life improved or was maintained in all patients. Adverse events and reductions in CD4+ T cell counts were consistent with those seen during alefacept monotherapy.

Original language	English
Pages (from-to)	424-427
Number of pages	4
Journal	Journal of Drugs in Dermatology
Volume	6
Issue number	4
State	Published - Apr 2007
Externally published	Yes

Cite this

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title = "An open-label study to evaluate the transition of patients with chronic plaque psoriasis from cyclosporine to alefacept.",

abstract = "Eleven patients with well-controlled psoriasis on cyclosporine (Physician's Global Assessment [PGA] of {"}mild{"} or better) participated in an open-label study that evaluated a strategy for transition to alefacept. Using this transition strategy, 7 of 11 patients (64\%) maintained PGA scores. Quality of life improved or was maintained in all patients. Adverse events and reductions in CD4+ T cell counts were consistent with those seen during alefacept monotherapy.",

author = "Magliocco, \{Melissa A.\} and Lozano, \{Ann Marie\} and \{Van Saders\}, Claudia and Schuler, \{Kristine W.\} and Gottlieb, \{Alice B.\}",

year = "2007",

month = apr,

language = "English",

volume = "6",

pages = "424--427",

journal = "Journal of Drugs in Dermatology",

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T1 - An open-label study to evaluate the transition of patients with chronic plaque psoriasis from cyclosporine to alefacept.

AU - Magliocco, Melissa A.

AU - Lozano, Ann Marie

AU - Van Saders, Claudia

AU - Schuler, Kristine W.

AU - Gottlieb, Alice B.

PY - 2007/4

Y1 - 2007/4

N2 - Eleven patients with well-controlled psoriasis on cyclosporine (Physician's Global Assessment [PGA] of "mild" or better) participated in an open-label study that evaluated a strategy for transition to alefacept. Using this transition strategy, 7 of 11 patients (64%) maintained PGA scores. Quality of life improved or was maintained in all patients. Adverse events and reductions in CD4+ T cell counts were consistent with those seen during alefacept monotherapy.

AB - Eleven patients with well-controlled psoriasis on cyclosporine (Physician's Global Assessment [PGA] of "mild" or better) participated in an open-label study that evaluated a strategy for transition to alefacept. Using this transition strategy, 7 of 11 patients (64%) maintained PGA scores. Quality of life improved or was maintained in all patients. Adverse events and reductions in CD4+ T cell counts were consistent with those seen during alefacept monotherapy.

UR - https://www.scopus.com/pages/publications/34548178999

M3 - Article

C2 - 17668540

AN - SCOPUS:34548178999

SN - 1545-9616

VL - 6

SP - 424

EP - 427

JO - Journal of Drugs in Dermatology

JF - Journal of Drugs in Dermatology

IS - 4

ER -

An open-label study to evaluate the transition of patients with chronic plaque psoriasis from cyclosporine to alefacept.

Abstract

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