An open-label study to evaluate the transition of patients with chronic plaque psoriasis from cyclosporine to alefacept.

Melissa A. Magliocco; Ann Marie Lozano; Claudia Van Saders; Kristine W. Schuler; Alice B. Gottlieb

An open-label study to evaluate the transition of patients with chronic plaque psoriasis from cyclosporine to alefacept.

Melissa A. Magliocco, Ann Marie Lozano, Claudia Van Saders, Kristine W. Schuler, Alice B. Gottlieb

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Eleven patients with well-controlled psoriasis on cyclosporine (Physician's Global Assessment [PGA] of "mild" or better) participated in an open-label study that evaluated a strategy for transition to alefacept. Using this transition strategy, 7 of 11 patients (64%) maintained PGA scores. Quality of life improved or was maintained in all patients. Adverse events and reductions in CD4+ T cell counts were consistent with those seen during alefacept monotherapy.

Original language	English
Pages (from-to)	424-427
Number of pages	4
Journal	Journal of Drugs in Dermatology
Volume	6
Issue number	4
State	Published - Apr 2007
Externally published	Yes

Cite this

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title = "An open-label study to evaluate the transition of patients with chronic plaque psoriasis from cyclosporine to alefacept.",

abstract = "Eleven patients with well-controlled psoriasis on cyclosporine (Physician's Global Assessment [PGA] of {"}mild{"} or better) participated in an open-label study that evaluated a strategy for transition to alefacept. Using this transition strategy, 7 of 11 patients (64%) maintained PGA scores. Quality of life improved or was maintained in all patients. Adverse events and reductions in CD4+ T cell counts were consistent with those seen during alefacept monotherapy.",

author = "Magliocco, {Melissa A.} and Lozano, {Ann Marie} and {Van Saders}, Claudia and Schuler, {Kristine W.} and Gottlieb, {Alice B.}",

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T1 - An open-label study to evaluate the transition of patients with chronic plaque psoriasis from cyclosporine to alefacept.

AU - Magliocco, Melissa A.

AU - Lozano, Ann Marie

AU - Van Saders, Claudia

AU - Schuler, Kristine W.

AU - Gottlieb, Alice B.

PY - 2007/4

Y1 - 2007/4

N2 - Eleven patients with well-controlled psoriasis on cyclosporine (Physician's Global Assessment [PGA] of "mild" or better) participated in an open-label study that evaluated a strategy for transition to alefacept. Using this transition strategy, 7 of 11 patients (64%) maintained PGA scores. Quality of life improved or was maintained in all patients. Adverse events and reductions in CD4+ T cell counts were consistent with those seen during alefacept monotherapy.

AB - Eleven patients with well-controlled psoriasis on cyclosporine (Physician's Global Assessment [PGA] of "mild" or better) participated in an open-label study that evaluated a strategy for transition to alefacept. Using this transition strategy, 7 of 11 patients (64%) maintained PGA scores. Quality of life improved or was maintained in all patients. Adverse events and reductions in CD4+ T cell counts were consistent with those seen during alefacept monotherapy.

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M3 - Article

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AN - SCOPUS:34548178999

SN - 1545-9616

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JF - Journal of Drugs in Dermatology

IS - 4

ER -

An open-label study to evaluate the transition of patients with chronic plaque psoriasis from cyclosporine to alefacept.

Abstract

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