Amygdalin binds to the CD4 receptor as suggested from molecular modeling studies

Oriol Llorens, Marta Filizola, Susanna Spisani, Mauro Marastoni, Concepcion Herranz, Juan J. Perez

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

The geometrical features of the proposed bioactive conformation of peptide T assessed by computational methods in a previous study, together with available structure-activity studies on peptide T, led us to propose a pharmacophore for the CD4-peptide T interaction. Subsequent, data base searching permitted us to identify amygdalin as a peptide T peptidomimetic.

Original languageEnglish
Pages (from-to)781-786
Number of pages6
JournalBioorganic and Medicinal Chemistry Letters
Volume8
Issue number7
DOIs
StatePublished - 7 Apr 1998
Externally publishedYes

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