Amniotic Membrane Patching to Assist Closure of Recalcitrant Macular Holes

Jessica Lee; Michael Chua; Michael Jansen; Jerome Giovinazzo; Brittany Powell; Avnish Deobhakta; Amanda Wong; Daniel Zhu; Philip J. Ferrone; Ronald Gentile; Gennady Landa; Alan Dayan; Aryeh Pollack; Richard Rosen

doi:10.3928/23258160-20230221-01

Amniotic Membrane Patching to Assist Closure of Recalcitrant Macular Holes

Jessica Lee, Michael Chua, Michael Jansen, Jerome Giovinazzo, Brittany Powell, Avnish Deobhakta, Amanda Wong, Daniel Zhu, Philip J. Ferrone, Ronald Gentile, Gennady Landa, Alan Dayan, Aryeh Pollack, Richard Rosen

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND AND OBJECTIVE: This study reports a case series of patients with persistent macular holes (MHs) who underwent human amniotic membrane subretinal placement to achieve successful anatomic MH closure. PATIENTS AND METHODS: This was a retrospective case series of patients with persistently open full-thickness MHs who underwent human amniotic membrane placement. Patients were observed up to 6 months postoperatively. RESULTS: Ten patients were included. The mean preoperative best-corrected visual acuity was 1.6 logMAR (20/800). Postoperatively, mean best-corrected visual acuity improved to 1.3 logMAR (20/400) at 1 month and 1.1 logMAR (20/250) by the 3- and 6-month visits. In all cases, the MH appeared closed at the 1-week visit and remained closed at their last follow-up. Optical coherence tomography showed closure in all cases. No adverse events were reported. CONCLUSIONS: Human amniotic membrane subretinal placement may serve as a useful surgical technique to assist in the closure of recalcitrant macular holes.

Original language	English
Pages (from-to)	218-222
Number of pages	5
Journal	Ophthalmic Surgery Lasers and Imaging Retina
Volume	54
Issue number	4
DOIs	https://doi.org/10.3928/23258160-20230221-01
State	Published - Apr 2023
Externally published	Yes

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@article{d0df005e3a8d4ebb98f0d3a9ef0370bb,

title = "Amniotic Membrane Patching to Assist Closure of Recalcitrant Macular Holes",

abstract = "BACKGROUND AND OBJECTIVE: This study reports a case series of patients with persistent macular holes (MHs) who underwent human amniotic membrane subretinal placement to achieve successful anatomic MH closure. PATIENTS AND METHODS: This was a retrospective case series of patients with persistently open full-thickness MHs who underwent human amniotic membrane placement. Patients were observed up to 6 months postoperatively. RESULTS: Ten patients were included. The mean preoperative best-corrected visual acuity was 1.6 logMAR (20/800). Postoperatively, mean best-corrected visual acuity improved to 1.3 logMAR (20/400) at 1 month and 1.1 logMAR (20/250) by the 3- and 6-month visits. In all cases, the MH appeared closed at the 1-week visit and remained closed at their last follow-up. Optical coherence tomography showed closure in all cases. No adverse events were reported. CONCLUSIONS: Human amniotic membrane subretinal placement may serve as a useful surgical technique to assist in the closure of recalcitrant macular holes.",

author = "Jessica Lee and Michael Chua and Michael Jansen and Jerome Giovinazzo and Brittany Powell and Avnish Deobhakta and Amanda Wong and Daniel Zhu and Ferrone, {Philip J.} and Ronald Gentile and Gennady Landa and Alan Dayan and Aryeh Pollack and Richard Rosen",

note = "Publisher Copyright: {\textcopyright} SLACK Incorporated.",

year = "2023",

month = apr,

doi = "10.3928/23258160-20230221-01",

language = "English",

volume = "54",

pages = "218--222",

journal = "Ophthalmic Surgery Lasers and Imaging Retina",

issn = "2325-8160",

publisher = "Slack Incorporated",

number = "4",

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TY - JOUR

T1 - Amniotic Membrane Patching to Assist Closure of Recalcitrant Macular Holes

AU - Lee, Jessica

AU - Chua, Michael

AU - Jansen, Michael

AU - Giovinazzo, Jerome

AU - Powell, Brittany

AU - Deobhakta, Avnish

AU - Wong, Amanda

AU - Zhu, Daniel

AU - Ferrone, Philip J.

AU - Gentile, Ronald

AU - Landa, Gennady

AU - Dayan, Alan

AU - Pollack, Aryeh

AU - Rosen, Richard

PY - 2023/4

Y1 - 2023/4

N2 - BACKGROUND AND OBJECTIVE: This study reports a case series of patients with persistent macular holes (MHs) who underwent human amniotic membrane subretinal placement to achieve successful anatomic MH closure. PATIENTS AND METHODS: This was a retrospective case series of patients with persistently open full-thickness MHs who underwent human amniotic membrane placement. Patients were observed up to 6 months postoperatively. RESULTS: Ten patients were included. The mean preoperative best-corrected visual acuity was 1.6 logMAR (20/800). Postoperatively, mean best-corrected visual acuity improved to 1.3 logMAR (20/400) at 1 month and 1.1 logMAR (20/250) by the 3- and 6-month visits. In all cases, the MH appeared closed at the 1-week visit and remained closed at their last follow-up. Optical coherence tomography showed closure in all cases. No adverse events were reported. CONCLUSIONS: Human amniotic membrane subretinal placement may serve as a useful surgical technique to assist in the closure of recalcitrant macular holes.

AB - BACKGROUND AND OBJECTIVE: This study reports a case series of patients with persistent macular holes (MHs) who underwent human amniotic membrane subretinal placement to achieve successful anatomic MH closure. PATIENTS AND METHODS: This was a retrospective case series of patients with persistently open full-thickness MHs who underwent human amniotic membrane placement. Patients were observed up to 6 months postoperatively. RESULTS: Ten patients were included. The mean preoperative best-corrected visual acuity was 1.6 logMAR (20/800). Postoperatively, mean best-corrected visual acuity improved to 1.3 logMAR (20/400) at 1 month and 1.1 logMAR (20/250) by the 3- and 6-month visits. In all cases, the MH appeared closed at the 1-week visit and remained closed at their last follow-up. Optical coherence tomography showed closure in all cases. No adverse events were reported. CONCLUSIONS: Human amniotic membrane subretinal placement may serve as a useful surgical technique to assist in the closure of recalcitrant macular holes.

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U2 - 10.3928/23258160-20230221-01

DO - 10.3928/23258160-20230221-01

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AN - SCOPUS:85152484533

SN - 2325-8160

VL - 54

SP - 218

EP - 222

JO - Ophthalmic Surgery Lasers and Imaging Retina

JF - Ophthalmic Surgery Lasers and Imaging Retina

IS - 4

ER -

Amniotic Membrane Patching to Assist Closure of Recalcitrant Macular Holes

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