Ambiente e obesidade no National Children's Study

Translated title of the contribution: Environment and obesity in the National Children's Study

Leonardo Trasande, Chris Cronk, Maureen Durkin, Marianne Weiss, Dale Schoeller, Elizabeth Gall, Jeanne Hewitt, Aaron Carrel, Philip Landrigan, Matthew Gillman

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


We describe the approach taken by the National Children's Study (NCS) to understanding the role of environmental factors in the development of obesity. We review the literature with regard to the two core hypotheses in the NCS that relate to environmental origins of obesity and describe strategies that will be used to test each hypothesis. Although it is clear that obesity in an individual results from an imbalance between energy intake and expenditure, control of the obesity epidemic will require understanding of factors in the modern built environment and chemical exposures that may have the capacity to disrupt the link between energy intake and expenditure. Through its embrace of the life-course approach to epidemiology, the NCS will be able to study the origins of obesity from preconception through late adolescence, including factors ranging from genetic inheritance to individual behaviors to the social, built, and natural environ-ment and chemical exposures. It will have sufficient statistical power to examine interactions among these multiple influences, including gene-environment and geneobesity interactions. A major sec-ondary benefit will derive from the banking of specimens for future analysis.

Translated title of the contributionEnvironment and obesity in the National Children's Study
Original languagePortuguese
Pages (from-to)195-210
Number of pages16
JournalCiencia e Saude Coletiva
Issue number1
StatePublished - 2010


  • Bisphenol a
  • Built environment
  • Diet
  • Endocrine disruptors
  • Obesity
  • Physical activity


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