Alloantigenic variant selection in vitro from a mouse lymphoma - Sarcoma hybrid

Tina Dalianis; Francis Wiener; George Klein

doi:10.1007/BF01564075

Alloantigenic variant selection in vitro from a mouse lymphoma - Sarcoma hybrid

Tina Dalianis, Francis Wiener, George Klein

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Abstract

Two H-2^a+/H-2^s - alloantigenic loss variants have been obtained from an H-2^a+/H-2^s+ mouse lymphoma/sarcoma hybrid, YACIR/MSWBS, by in vitro selection, with repeated exposure to anti-H-2^s serum and complement. Loss of the MSWBS derived H-2^s complex was associated with the loss of the morphologically distinguishable, translocated MSWBS derived chromosomes 17. The morphologically normal YACIR-derived chromosomes 17 were maintained.

Original language	English
Pages (from-to)	370-397
Number of pages	28
Journal	Immunogenetics
Volume	1
Issue number	1
DOIs	https://doi.org/10.1007/BF01564075
State	Published - Dec 1974
Externally published	Yes

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title = "Alloantigenic variant selection in vitro from a mouse lymphoma - Sarcoma hybrid",

abstract = "Two H-2a+/H-2s - alloantigenic loss variants have been obtained from an H-2a+/H-2s+ mouse lymphoma/sarcoma hybrid, YACIR/MSWBS, by in vitro selection, with repeated exposure to anti-H-2s serum and complement. Loss of the MSWBS derived H-2s complex was associated with the loss of the morphologically distinguishable, translocated MSWBS derived chromosomes 17. The morphologically normal YACIR-derived chromosomes 17 were maintained.",

author = "Tina Dalianis and Francis Wiener and George Klein",

year = "1974",

month = dec,

doi = "10.1007/BF01564075",

language = "English",

volume = "1",

pages = "370--397",

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T1 - Alloantigenic variant selection in vitro from a mouse lymphoma - Sarcoma hybrid

AU - Dalianis, Tina

AU - Wiener, Francis

AU - Klein, George

PY - 1974/12

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N2 - Two H-2a+/H-2s - alloantigenic loss variants have been obtained from an H-2a+/H-2s+ mouse lymphoma/sarcoma hybrid, YACIR/MSWBS, by in vitro selection, with repeated exposure to anti-H-2s serum and complement. Loss of the MSWBS derived H-2s complex was associated with the loss of the morphologically distinguishable, translocated MSWBS derived chromosomes 17. The morphologically normal YACIR-derived chromosomes 17 were maintained.

AB - Two H-2a+/H-2s - alloantigenic loss variants have been obtained from an H-2a+/H-2s+ mouse lymphoma/sarcoma hybrid, YACIR/MSWBS, by in vitro selection, with repeated exposure to anti-H-2s serum and complement. Loss of the MSWBS derived H-2s complex was associated with the loss of the morphologically distinguishable, translocated MSWBS derived chromosomes 17. The morphologically normal YACIR-derived chromosomes 17 were maintained.

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VL - 1

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JO - Immunogenetics

JF - Immunogenetics

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ER -

Alloantigenic variant selection in vitro from a mouse lymphoma - Sarcoma hybrid

Abstract

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