Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013

Peter G. Passias; Cole Bortz; Haddy Alas; Frank A. Segreto; Samantha R. Horn; Yael U. Ihejirika; Dennis Vasquez-Montes; Katherine E. Pierce; Avery E. Brown; Kartik Shenoy; Edward M. DelSole; Bradley Johnson; Cheongeun Oh; Peter L. Zhou; Chloe Deflorimonte; Ekhamjeet S. Dhillon; Pawel P. Jankowski; Bassel G. Diebo; Virginie Lafage; Renaud Lafage; Shaleen N. Vira; John A. Bendo; Jeffrey A. Goldstein; Frank J. Schwab; Michael C. Gerling

doi:10.1016/j.jor.2018.12.011

Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013

Peter G. Passias
, Cole Bortz
, Haddy Alas
, Frank A. Segreto
, Samantha R. Horn
, Yael U. Ihejirika
, Dennis Vasquez-Montes
, Katherine E. Pierce
, Avery E. Brown
, Kartik Shenoy
, Edward M. DelSole
, Bradley Johnson
, Cheongeun Oh
, Peter L. Zhou
, Chloe Deflorimonte
, Ekhamjeet S. Dhillon
, Pawel P. Jankowski
, Bassel G. Diebo
, Virginie Lafage
, Renaud Lafage

Shaleen N. Vira, John A. Bendo, Jeffrey A. Goldstein, Frank J. Schwab, Michael C. Gerling

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Introduction: This study assessed the incidence and risk factors for pseudarthrosis among primary spine fusion patients. Methods: Retrospective review of ACS-NSQIP (2005–2013). Differences in comorbidities between spine fusion patients with and without pseudarthrosis (Pseud, N-Pseud) were assessed using chi-squared tests and Independent Samples t-tests. Binary logistic regression assessed patient-related and procedure-related predictors for pseudarthrosis. Results: 52,402 patients (57yrs, 53%F, 0.4% w/pseudarthrosis). Alcohol consumption (OR:2.6[1.2–5.7]) and prior history of surgical revision (OR:1.6[1.4–1.8]) were risk factors for pseudarthrosis operation. Pseud patients at higher risk for deep incisional SSI (at 30-days:OR:6.6[2.0–21.8]). Pseud patients had more perioperative complications (avg:0.24 ± 0.43v0.18 ± 0.39,p=0.026). Conclusions: Alcoholism and surgical revision are major risk factors for pseudarthrosis in patients undergoing spine fusion.

Original language	English
Pages (from-to)	36-40
Number of pages	5
Journal	Journal of Orthopaedics
Volume	16
Issue number	1
DOIs	https://doi.org/10.1016/j.jor.2018.12.011
State	Published - 1 Jan 2019
Externally published	Yes

Keywords

30-Day complication rates
Alcoholism
Predictors
Primary spine fusion
Pseudarthrosis
Surgical revision

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10.1016/j.jor.2018.12.011

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Passias, P. G., Bortz, C., Alas, H., Segreto, F. A., Horn, S. R., Ihejirika, Y. U., Vasquez-Montes, D., Pierce, K. E., Brown, A. E., Shenoy, K., DelSole, E. M., Johnson, B., Oh, C., Zhou, P. L., Deflorimonte, C., Dhillon, E. S., Jankowski, P. P., Diebo, B. G., Lafage, V., ... Gerling, M. C. (2019). Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013. Journal of Orthopaedics, 16(1), 36-40. https://doi.org/10.1016/j.jor.2018.12.011

@article{5b08ad98b6624579bb9764549bf2f581,

title = "Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013",

abstract = "Introduction: This study assessed the incidence and risk factors for pseudarthrosis among primary spine fusion patients. Methods: Retrospective review of ACS-NSQIP (2005–2013). Differences in comorbidities between spine fusion patients with and without pseudarthrosis (Pseud, N-Pseud) were assessed using chi-squared tests and Independent Samples t-tests. Binary logistic regression assessed patient-related and procedure-related predictors for pseudarthrosis. Results: 52,402 patients (57yrs, 53\%F, 0.4\% w/pseudarthrosis). Alcohol consumption (OR:2.6[1.2–5.7]) and prior history of surgical revision (OR:1.6[1.4–1.8]) were risk factors for pseudarthrosis operation. Pseud patients at higher risk for deep incisional SSI (at 30-days:OR:6.6[2.0–21.8]). Pseud patients had more perioperative complications (avg:0.24 ± 0.43v0.18 ± 0.39,p=0.026). Conclusions: Alcoholism and surgical revision are major risk factors for pseudarthrosis in patients undergoing spine fusion.",

keywords = "30-Day complication rates, Alcoholism, Predictors, Primary spine fusion, Pseudarthrosis, Surgical revision",

author = "Passias, \{Peter G.\} and Cole Bortz and Haddy Alas and Segreto, \{Frank A.\} and Horn, \{Samantha R.\} and Ihejirika, \{Yael U.\} and Dennis Vasquez-Montes and Pierce, \{Katherine E.\} and Brown, \{Avery E.\} and Kartik Shenoy and DelSole, \{Edward M.\} and Bradley Johnson and Cheongeun Oh and Zhou, \{Peter L.\} and Chloe Deflorimonte and Dhillon, \{Ekhamjeet S.\} and Jankowski, \{Pawel P.\} and Diebo, \{Bassel G.\} and Virginie Lafage and Renaud Lafage and Vira, \{Shaleen N.\} and Bendo, \{John A.\} and Goldstein, \{Jeffrey A.\} and Schwab, \{Frank J.\} and Gerling, \{Michael C.\}",

note = "Publisher Copyright: {\textcopyright} 2018 Prof. PK Surendran Memorial Education Foundation",

year = "2019",

month = jan,

day = "1",

doi = "10.1016/j.jor.2018.12.011",

language = "English",

volume = "16",

pages = "36--40",

journal = "Journal of Orthopaedics",

issn = "0972-978X",

publisher = "Reed Elsevier India Pvt. Ltd.",

number = "1",

}

Passias, PG, Bortz, C, Alas, H, Segreto, FA, Horn, SR, Ihejirika, YU, Vasquez-Montes, D, Pierce, KE, Brown, AE, Shenoy, K, DelSole, EM, Johnson, B, Oh, C, Zhou, PL, Deflorimonte, C, Dhillon, ES, Jankowski, PP, Diebo, BG, Lafage, V, Lafage, R, Vira, SN, Bendo, JA, Goldstein, JA, Schwab, FJ & Gerling, MC 2019, 'Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013', Journal of Orthopaedics, vol. 16, no. 1, pp. 36-40. https://doi.org/10.1016/j.jor.2018.12.011

TY - JOUR

T1 - Alcoholism as a predictor for pseudarthrosis in primary spine fusion

T2 - An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013

AU - Passias, Peter G.

AU - Bortz, Cole

AU - Alas, Haddy

AU - Segreto, Frank A.

AU - Horn, Samantha R.

AU - Ihejirika, Yael U.

AU - Vasquez-Montes, Dennis

AU - Pierce, Katherine E.

AU - Brown, Avery E.

AU - Shenoy, Kartik

AU - DelSole, Edward M.

AU - Johnson, Bradley

AU - Oh, Cheongeun

AU - Zhou, Peter L.

AU - Deflorimonte, Chloe

AU - Dhillon, Ekhamjeet S.

AU - Jankowski, Pawel P.

AU - Diebo, Bassel G.

AU - Lafage, Virginie

AU - Lafage, Renaud

AU - Vira, Shaleen N.

AU - Bendo, John A.

AU - Goldstein, Jeffrey A.

AU - Schwab, Frank J.

AU - Gerling, Michael C.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Introduction: This study assessed the incidence and risk factors for pseudarthrosis among primary spine fusion patients. Methods: Retrospective review of ACS-NSQIP (2005–2013). Differences in comorbidities between spine fusion patients with and without pseudarthrosis (Pseud, N-Pseud) were assessed using chi-squared tests and Independent Samples t-tests. Binary logistic regression assessed patient-related and procedure-related predictors for pseudarthrosis. Results: 52,402 patients (57yrs, 53%F, 0.4% w/pseudarthrosis). Alcohol consumption (OR:2.6[1.2–5.7]) and prior history of surgical revision (OR:1.6[1.4–1.8]) were risk factors for pseudarthrosis operation. Pseud patients at higher risk for deep incisional SSI (at 30-days:OR:6.6[2.0–21.8]). Pseud patients had more perioperative complications (avg:0.24 ± 0.43v0.18 ± 0.39,p=0.026). Conclusions: Alcoholism and surgical revision are major risk factors for pseudarthrosis in patients undergoing spine fusion.

AB - Introduction: This study assessed the incidence and risk factors for pseudarthrosis among primary spine fusion patients. Methods: Retrospective review of ACS-NSQIP (2005–2013). Differences in comorbidities between spine fusion patients with and without pseudarthrosis (Pseud, N-Pseud) were assessed using chi-squared tests and Independent Samples t-tests. Binary logistic regression assessed patient-related and procedure-related predictors for pseudarthrosis. Results: 52,402 patients (57yrs, 53%F, 0.4% w/pseudarthrosis). Alcohol consumption (OR:2.6[1.2–5.7]) and prior history of surgical revision (OR:1.6[1.4–1.8]) were risk factors for pseudarthrosis operation. Pseud patients at higher risk for deep incisional SSI (at 30-days:OR:6.6[2.0–21.8]). Pseud patients had more perioperative complications (avg:0.24 ± 0.43v0.18 ± 0.39,p=0.026). Conclusions: Alcoholism and surgical revision are major risk factors for pseudarthrosis in patients undergoing spine fusion.

KW - 30-Day complication rates

KW - Alcoholism

KW - Predictors

KW - Primary spine fusion

KW - Pseudarthrosis

KW - Surgical revision

UR - https://www.scopus.com/pages/publications/85058789258

U2 - 10.1016/j.jor.2018.12.011

DO - 10.1016/j.jor.2018.12.011

M3 - Article

AN - SCOPUS:85058789258

SN - 0972-978X

VL - 16

SP - 36

EP - 40

JO - Journal of Orthopaedics

JF - Journal of Orthopaedics

IS - 1

ER -

Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013

Abstract

Keywords

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