Alcohol: basic and translational research; 15th annual Charles Lieber &1st Samuel French satellite symposium

Manuela G. Neuman; Helmut K. Seitz; Pamela L. Tuma; Natalia A. Osna; Carol A. Casey; Kusum K. Kharbanda; Lawrence B. Cohen; Steve D.H. Malnick; Raghabendra Adhikari; Ramyajit Mitra; Raghubendra Singh Dagur; Murali Ganesan; Chava Srinivas; Arumugam Madan Kumar; Moses New-Aaron; Larisa Poluektova; Paul G. Thomes; Karuna Rasineni; Mihai Opris; Rolf Teschke

doi:10.1016/j.yexmp.2022.104750

Alcohol: basic and translational research; 15th annual Charles Lieber &1st Samuel French satellite symposium

Manuela G. Neuman, Helmut K. Seitz, Pamela L. Tuma, Natalia A. Osna, Carol A. Casey, Kusum K. Kharbanda, Lawrence B. Cohen, Steve D.H. Malnick, Raghabendra Adhikari, Ramyajit Mitra, Raghubendra Singh Dagur, Murali Ganesan, Chava Srinivas, Arumugam Madan Kumar, Moses New-Aaron, Larisa Poluektova, Paul G. Thomes, Karuna Rasineni, Mihai Opris, Rolf Teschke

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Abstract

The present review is based on the research presented at the symposium dedicated to the legacy of the two scientists that made important discoveries in the field of alcohol-induced liver damage: Professors C.S. Lieber and S.W. French. The invited speakers described pharmacological, toxicological and patho-physiological effects of alcohol misuse. Moreover, genetic biomarkers determining adverse drug reactions due to interactions between therapeutics used for chronic or infectious diseases and alcohol exposure were discussed. The researchers presented their work in areas of alcohol-induced impairment in lipid protein trafficking and endocytosis, as well as the role of lipids in the development of fatty liver. The researchers showed that alcohol leads to covalent modifications that promote hepatic dysfunction and injury. We concluded that using new advanced techniques and research ideas leads to important discoveries in science.

Original language	English
Article number	104750
Journal	Experimental and Molecular Pathology
Volume	126
DOIs	https://doi.org/10.1016/j.yexmp.2022.104750
State	Published - Jun 2022
Externally published	Yes

Keywords

Acetylation
Alcoholic liver disease
Human immunodeficiency virus
Hyaline Bodies, Lipid and protein traffic
Inflammation
Nonalcoholic liver disease
Nutrition
Tissue culture

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10.1016/j.yexmp.2022.104750

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Neuman, M. G., Seitz, H. K., Tuma, P. L., Osna, N. A., Casey, C. A., Kharbanda, K. K., Cohen, L. B., Malnick, S. D. H., Adhikari, R., Mitra, R., Dagur, R. S., Ganesan, M., Srinivas, C., Madan Kumar, A., New-Aaron, M., Poluektova, L., Thomes, P. G., Rasineni, K., Opris, M., & Teschke, R. (2022). Alcohol: basic and translational research; 15th annual Charles Lieber &1st Samuel French satellite symposium. Experimental and Molecular Pathology, 126, Article 104750. https://doi.org/10.1016/j.yexmp.2022.104750

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title = "Alcohol: basic and translational research; 15th annual Charles Lieber &1st Samuel French satellite symposium",

abstract = "The present review is based on the research presented at the symposium dedicated to the legacy of the two scientists that made important discoveries in the field of alcohol-induced liver damage: Professors C.S. Lieber and S.W. French. The invited speakers described pharmacological, toxicological and patho-physiological effects of alcohol misuse. Moreover, genetic biomarkers determining adverse drug reactions due to interactions between therapeutics used for chronic or infectious diseases and alcohol exposure were discussed. The researchers presented their work in areas of alcohol-induced impairment in lipid protein trafficking and endocytosis, as well as the role of lipids in the development of fatty liver. The researchers showed that alcohol leads to covalent modifications that promote hepatic dysfunction and injury. We concluded that using new advanced techniques and research ideas leads to important discoveries in science.",

keywords = "Acetylation, Alcoholic liver disease, Human immunodeficiency virus, Hyaline Bodies, Lipid and protein traffic, Inflammation, Nonalcoholic liver disease, Nutrition, Tissue culture",

author = "Neuman, {Manuela G.} and Seitz, {Helmut K.} and Tuma, {Pamela L.} and Osna, {Natalia A.} and Casey, {Carol A.} and Kharbanda, {Kusum K.} and Cohen, {Lawrence B.} and Malnick, {Steve D.H.} and Raghabendra Adhikari and Ramyajit Mitra and Dagur, {Raghubendra Singh} and Murali Ganesan and Chava Srinivas and {Madan Kumar}, Arumugam and Moses New-Aaron and Larisa Poluektova and Thomes, {Paul G.} and Karuna Rasineni and Mihai Opris and Rolf Teschke",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier Inc.",

year = "2022",

month = jun,

doi = "10.1016/j.yexmp.2022.104750",

language = "English",

volume = "126",

journal = "Experimental and Molecular Pathology",

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Neuman, MG, Seitz, HK, Tuma, PL, Osna, NA, Casey, CA, Kharbanda, KK, Cohen, LB, Malnick, SDH, Adhikari, R, Mitra, R, Dagur, RS, Ganesan, M, Srinivas, C, Madan Kumar, A, New-Aaron, M, Poluektova, L, Thomes, PG, Rasineni, K, Opris, M & Teschke, R 2022, 'Alcohol: basic and translational research; 15th annual Charles Lieber &1st Samuel French satellite symposium', Experimental and Molecular Pathology, vol. 126, 104750. https://doi.org/10.1016/j.yexmp.2022.104750

TY - JOUR

T1 - Alcohol

T2 - basic and translational research; 15th annual Charles Lieber &1st Samuel French satellite symposium

AU - Neuman, Manuela G.

AU - Seitz, Helmut K.

AU - Tuma, Pamela L.

AU - Osna, Natalia A.

AU - Casey, Carol A.

AU - Kharbanda, Kusum K.

AU - Cohen, Lawrence B.

AU - Malnick, Steve D.H.

AU - Adhikari, Raghabendra

AU - Mitra, Ramyajit

AU - Dagur, Raghubendra Singh

AU - Ganesan, Murali

AU - Srinivas, Chava

AU - Madan Kumar, Arumugam

AU - New-Aaron, Moses

AU - Poluektova, Larisa

AU - Thomes, Paul G.

AU - Rasineni, Karuna

AU - Opris, Mihai

AU - Teschke, Rolf

PY - 2022/6

Y1 - 2022/6

N2 - The present review is based on the research presented at the symposium dedicated to the legacy of the two scientists that made important discoveries in the field of alcohol-induced liver damage: Professors C.S. Lieber and S.W. French. The invited speakers described pharmacological, toxicological and patho-physiological effects of alcohol misuse. Moreover, genetic biomarkers determining adverse drug reactions due to interactions between therapeutics used for chronic or infectious diseases and alcohol exposure were discussed. The researchers presented their work in areas of alcohol-induced impairment in lipid protein trafficking and endocytosis, as well as the role of lipids in the development of fatty liver. The researchers showed that alcohol leads to covalent modifications that promote hepatic dysfunction and injury. We concluded that using new advanced techniques and research ideas leads to important discoveries in science.

AB - The present review is based on the research presented at the symposium dedicated to the legacy of the two scientists that made important discoveries in the field of alcohol-induced liver damage: Professors C.S. Lieber and S.W. French. The invited speakers described pharmacological, toxicological and patho-physiological effects of alcohol misuse. Moreover, genetic biomarkers determining adverse drug reactions due to interactions between therapeutics used for chronic or infectious diseases and alcohol exposure were discussed. The researchers presented their work in areas of alcohol-induced impairment in lipid protein trafficking and endocytosis, as well as the role of lipids in the development of fatty liver. The researchers showed that alcohol leads to covalent modifications that promote hepatic dysfunction and injury. We concluded that using new advanced techniques and research ideas leads to important discoveries in science.

KW - Acetylation

KW - Alcoholic liver disease

KW - Human immunodeficiency virus

KW - Hyaline Bodies, Lipid and protein traffic

KW - Inflammation

KW - Nonalcoholic liver disease

KW - Nutrition

KW - Tissue culture

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U2 - 10.1016/j.yexmp.2022.104750

DO - 10.1016/j.yexmp.2022.104750

M3 - Review article

C2 - 35192844

AN - SCOPUS:85127713965

SN - 0014-4800

VL - 126

JO - Experimental and Molecular Pathology

JF - Experimental and Molecular Pathology

M1 - 104750

ER -

Alcohol: basic and translational research; 15th annual Charles Lieber &1st Samuel French satellite symposium

Abstract

Keywords

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