[Aib5,6-D-Ala8]-cyclolinopeptide A, grown from a benzene/acetonitrile mixture.

M. Saviano, F. Rossi, M. Filizola, B. Di Blasio, C. Pedone

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

cyclo-(Prolyl-prolyl-phenylalanyl-phenylalanyl- alpha-aminoisobutyryl-alpha-aminoisobutyryl-isoleucyl-D-alan yl-valyl) ([Aib5,6-D-Ala8]-cyclolinopeptide A), grown from benzene/acetonitrile mixture, crystallizes with one acetonitrile and two water molecules. The molecular structure is almost identical to that obtained from methanol/water. The dimension of the solvent channels found in these structures is reduced in the present one, but the intramolecular hydrogen-bond pattern is preserved. The Pro1-Pro2 peptide unit is cis (omega = 8 degrees); all others are trans.

Original languageEnglish
Pages (from-to)663-666
Number of pages4
JournalActa crystallographica. Section C, Crystal structure communications
Volume51 ( Pt 4)
DOIs
StatePublished - 15 Apr 1995
Externally publishedYes

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