Aging kidney: Modern perspectives for an 'old' problem

Fabrizio Grosjean, Helen Vlassara, Gary E. Striker

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

The scientific community and health systems will have to address the increasing incidence of reduced kidney function because of progressive global aging. The aim of this review is to describe the morphological and functional alterations that characterize the aging kidney and to suggest not only pharmaceutical pathways but also lifestyle changes that could be beneficially targeted.

Original languageEnglish
Pages (from-to)737-748
Number of pages12
JournalAging Health
Volume7
Issue number5
DOIs
StatePublished - Oct 2011

Keywords

  • AGER1
  • Klotho
  • SIRT1
  • advanced glycation end product
  • aging kidney
  • chronic kidney disease
  • diet
  • mTOR
  • oxidant stress

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