Aging and HIV/AIDS: Neurocognitive implications for older HIV-positive Latina/o adults

Monica Rivera Mindt; Caitlin Miranda; Alyssa Arentoft; Desiree Byrd; Jennifer Monzones; Armando Fuentes; Francesca Arias; Miguel Arce Rentería; Ana Rosario; Susan Morgello

doi:10.1080/08964289.2014.914464

Aging and HIV/AIDS: Neurocognitive implications for older HIV-positive Latina/o adults

Monica Rivera Mindt, Caitlin Miranda, Alyssa Arentoft, Desiree Byrd, Jennifer Monzones, Armando Fuentes, Francesca Arias, Miguel Arce Rentería, Ana Rosario, Susan Morgello

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

In recent years, HIV/AIDS populations have become older and increasingly more ethnically diverse. Concurrently, the prevalence of HIV-related neurocognitive (NC) impairment remains high. This study examined the effects of age and ethnicity on NC function in HIV-positive adults. The sample (N = 126; 84 Latina/o and 42 Non-Hispanic White) completed a comprehensive NC battery. Global NC and domain average demographically-corrected t-scores were generated. There were no significant differences between Younger (<50 years) Latina/os and non-Hispanic Whites on Global NC function or NC domains (all p's >.10), with generally small effect sizes. Older Latina/os (≥50 years) were significantly more impaired than Older Non-Hispanic Whites on processing speed and learning, with trends in Global NC function and memory. Further, effect sizes fell within the medium to large range (Cohen's d's =.49-1.15). This study suggests that older Latina/os are at potentially greater risk for NC impairment, particularly in processing speed and learning, when compared to similarly-aged non-Hispanic whites. © 2014

Original language	English
Pages (from-to)	116-123
Number of pages	8
Journal	Behavioral Medicine
Volume	40
Issue number	3
DOIs	https://doi.org/10.1080/08964289.2014.914464
State	Published - 3 Jul 2014
Externally published	Yes

Keywords

AIDS
HAND
HIV
Hispanics
Latina/os
aging
cognition
health disparities
neurocognitive
neuropsychological impairment

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10.1080/08964289.2014.914464

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title = "Aging and HIV/AIDS: Neurocognitive implications for older HIV-positive Latina/o adults",

abstract = "In recent years, HIV/AIDS populations have become older and increasingly more ethnically diverse. Concurrently, the prevalence of HIV-related neurocognitive (NC) impairment remains high. This study examined the effects of age and ethnicity on NC function in HIV-positive adults. The sample (N = 126; 84 Latina/o and 42 Non-Hispanic White) completed a comprehensive NC battery. Global NC and domain average demographically-corrected t-scores were generated. There were no significant differences between Younger (<50 years) Latina/os and non-Hispanic Whites on Global NC function or NC domains (all p's >.10), with generally small effect sizes. Older Latina/os (≥50 years) were significantly more impaired than Older Non-Hispanic Whites on processing speed and learning, with trends in Global NC function and memory. Further, effect sizes fell within the medium to large range (Cohen's d's =.49-1.15). This study suggests that older Latina/os are at potentially greater risk for NC impairment, particularly in processing speed and learning, when compared to similarly-aged non-Hispanic whites. {\textcopyright} 2014",

keywords = "AIDS, HAND, HIV, Hispanics, Latina/os, aging, cognition, health disparities, neurocognitive, neuropsychological impairment",

author = "Mindt, {Monica Rivera} and Caitlin Miranda and Alyssa Arentoft and Desiree Byrd and Jennifer Monzones and Armando Fuentes and Francesca Arias and Renter{\'i}a, {Miguel Arce} and Ana Rosario and Susan Morgello",

note = "Funding Information: This research was supported by K23MH07971801 and an Early Career Development Award from the Northeast Consortium for Minority Faculty Development (to MRM); R24MH59724 and U01MH083501 (to SM); N01MH22005 (Igor Grant PI, subcontract to SM); and by the Clinical Research Center of the Mount Sinai School of Medicine (M01-RR00071).",

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AU - Mindt, Monica Rivera

AU - Miranda, Caitlin

AU - Arentoft, Alyssa

AU - Byrd, Desiree

AU - Monzones, Jennifer

AU - Fuentes, Armando

AU - Arias, Francesca

AU - Rentería, Miguel Arce

AU - Rosario, Ana

AU - Morgello, Susan

N1 - Funding Information: This research was supported by K23MH07971801 and an Early Career Development Award from the Northeast Consortium for Minority Faculty Development (to MRM); R24MH59724 and U01MH083501 (to SM); N01MH22005 (Igor Grant PI, subcontract to SM); and by the Clinical Research Center of the Mount Sinai School of Medicine (M01-RR00071).

PY - 2014/7/3

Y1 - 2014/7/3

N2 - In recent years, HIV/AIDS populations have become older and increasingly more ethnically diverse. Concurrently, the prevalence of HIV-related neurocognitive (NC) impairment remains high. This study examined the effects of age and ethnicity on NC function in HIV-positive adults. The sample (N = 126; 84 Latina/o and 42 Non-Hispanic White) completed a comprehensive NC battery. Global NC and domain average demographically-corrected t-scores were generated. There were no significant differences between Younger (<50 years) Latina/os and non-Hispanic Whites on Global NC function or NC domains (all p's >.10), with generally small effect sizes. Older Latina/os (≥50 years) were significantly more impaired than Older Non-Hispanic Whites on processing speed and learning, with trends in Global NC function and memory. Further, effect sizes fell within the medium to large range (Cohen's d's =.49-1.15). This study suggests that older Latina/os are at potentially greater risk for NC impairment, particularly in processing speed and learning, when compared to similarly-aged non-Hispanic whites. © 2014

AB - In recent years, HIV/AIDS populations have become older and increasingly more ethnically diverse. Concurrently, the prevalence of HIV-related neurocognitive (NC) impairment remains high. This study examined the effects of age and ethnicity on NC function in HIV-positive adults. The sample (N = 126; 84 Latina/o and 42 Non-Hispanic White) completed a comprehensive NC battery. Global NC and domain average demographically-corrected t-scores were generated. There were no significant differences between Younger (<50 years) Latina/os and non-Hispanic Whites on Global NC function or NC domains (all p's >.10), with generally small effect sizes. Older Latina/os (≥50 years) were significantly more impaired than Older Non-Hispanic Whites on processing speed and learning, with trends in Global NC function and memory. Further, effect sizes fell within the medium to large range (Cohen's d's =.49-1.15). This study suggests that older Latina/os are at potentially greater risk for NC impairment, particularly in processing speed and learning, when compared to similarly-aged non-Hispanic whites. © 2014

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KW - cognition

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ER -

Aging and HIV/AIDS: Neurocognitive implications for older HIV-positive Latina/o adults

Abstract

Keywords

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