TY - JOUR
T1 - Aging and HIV infection
AU - Kohli, Rakhi
AU - Klein, Robert S.
AU - Schoenbaum, Ellie E.
AU - Anastos, Kathryn
AU - Minkoff, Howard
AU - Sacks, Henry S.
N1 - Funding Information:
Data in this manuscript were collected by the Women’s Interagency HIV Study (WIHS) Collaborative Study Group with centers (Principal Investigators) at New York City/Bronx Consortium (Kathryn Anastos); Brooklyn, NY (Howard Minkoff); Washington DC Metropolitan Consortium (Mary Young); The Connie Wofsy Study Consortium of Northern California (Ruth Greenblatt); Los Angeles County/ Southern California Consortium (Alexandra Levine); Chicago Consortium (Mardge Cohen); Data Coordinating Center (Stephen Gange). The WIHS is funded by the National Institute of Allergy and Infectious Diseases with supplemental funding from the National Cancer Institute, the National Institute on Drug Abuse (UO1-AI-35004, UO1-AI-31834, UO1-AI-34994, UO1-AI-34989, UO1-AI-34993, and UO1-AI-42590). Data were also included from the Natural History of HIV Infection in Intravenous Drug Users (R01DA04347 – PI Ellie E Schoenbaum), Natural History of Menopause in HIV-Infected Drug Users (R01DA0135 – PI Ellie E Schoenbaum), Atherosclerosis, Bone Loss, Drug Use, and HIV in Older Men (R01DA014998 – PI Robert S Klein) all funded by the National Institute on Drug Abuse. Funding is also provided by the National Institute of Child Health and Human Development (UO1-CH-32632) the National Center for Research Resources (MO1-RR-00071, MO1-RR-00079, MO1-RR-00083).
PY - 2006/1
Y1 - 2006/1
N2 - With the advent of highly active antiretroviral therapy (HAART) in mid-1995, the prognosis for HIV-infected individuals has brightened dramatically. However, the conjunction of potent antiviral therapy and longer life expectancy may engender a variety of health risks that, heretofore, HIV specialists have not had to confront. The long-term effects of HIV infection itself and exposure to antiretroviral agents is unknown. Several aspects of aging, including psychiatric disease, neurocognitive impairment, and metabolic and hormonal disorders, may be influenced by chronic exposure to HIV and/or HIV therapeutics. In this paper, we discuss the health issues confronting HIV-infected older adults and areas for future research.
AB - With the advent of highly active antiretroviral therapy (HAART) in mid-1995, the prognosis for HIV-infected individuals has brightened dramatically. However, the conjunction of potent antiviral therapy and longer life expectancy may engender a variety of health risks that, heretofore, HIV specialists have not had to confront. The long-term effects of HIV infection itself and exposure to antiretroviral agents is unknown. Several aspects of aging, including psychiatric disease, neurocognitive impairment, and metabolic and hormonal disorders, may be influenced by chronic exposure to HIV and/or HIV therapeutics. In this paper, we discuss the health issues confronting HIV-infected older adults and areas for future research.
KW - Aging
KW - HAART
KW - HIV infection
KW - Substance abuse
UR - https://www.scopus.com/pages/publications/33745014210
U2 - 10.1007/s11524-005-9005-6
DO - 10.1007/s11524-005-9005-6
M3 - Article
C2 - 16736353
AN - SCOPUS:33745014210
SN - 1099-3460
VL - 83
SP - 31
EP - 42
JO - Journal of Urban Health
JF - Journal of Urban Health
IS - 1
ER -