TY - JOUR
T1 - Aggravation of Diabetic Hyperglycemia by Chlordiazepoxide
AU - Zumoff, Barnett
AU - Hellman, Leon
PY - 1977/5/2
Y1 - 1977/5/2
N2 - The administration of chlordiazepoxide hydrochloride, 40 mg daily, aggravated the hyperglycemia in an insulin-dependent, maturity-onset diabetic woman, raising the fasting blood glucose values from 220 mg/100 ml to 380 mg/100 ml. Review of the literature shows that virtually all psychoactive drugs affect diabetes; most tranquilizers aggravate diabetic hyperglycemia, while most antidepressants ameliorate it. The effect described in this communication is of clinical importance because of the widespread use of the benzodiazepine tranquilizers.
AB - The administration of chlordiazepoxide hydrochloride, 40 mg daily, aggravated the hyperglycemia in an insulin-dependent, maturity-onset diabetic woman, raising the fasting blood glucose values from 220 mg/100 ml to 380 mg/100 ml. Review of the literature shows that virtually all psychoactive drugs affect diabetes; most tranquilizers aggravate diabetic hyperglycemia, while most antidepressants ameliorate it. The effect described in this communication is of clinical importance because of the widespread use of the benzodiazepine tranquilizers.
UR - http://www.scopus.com/inward/record.url?scp=0017402982&partnerID=8YFLogxK
U2 - 10.1001/jama.1977.03270450050019
DO - 10.1001/jama.1977.03270450050019
M3 - Article
C2 - 576708
AN - SCOPUS:0017402982
SN - 0098-7484
VL - 237
SP - 1960
EP - 1961
JO - JAMA - Journal of the American Medical Association
JF - JAMA - Journal of the American Medical Association
IS - 18
ER -