Age-specific ovarian function

Norbert Gleicher, Andrea Weghofer, David H. Barad

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

It has been suggested that approximately 10% of females demonstrate premature ovarian aging. In younger women the diagnosis is frequently overlooked, since ovarian function parameters often still lie within ranges that are traditionally considered normal. Age-specific ovarian testing normalizes ovarian function parameters according to age. Such testing can, therefore, detect subtle ovarian abnormalities at earlier stages. Timely diagnosis of premature ovarian aging mandates the understanding of age-specific ovarian function testing. Among active infertility patients such testing reveals a far higher prevalence of premature ovarian aging risk than in a general population, the highest in youngest patients and a declining risk as women age. Since patient populations at different fertility centers vary in severity of ovarian compromise, center-based, age-specific ovarian function tests are not universally applicable. Such universally applicable function tests can only be defined in normal, fertile populations and their establishment should become a priority for the profession.

Original languageEnglish
Pages (from-to)595-600
Number of pages6
JournalExpert Review of Obstetrics and Gynecology
Volume3
Issue number5
DOIs
StatePublished - Sep 2008
Externally publishedYes

Keywords

  • Age
  • Diminished ovarian reserve
  • Follicle stimulating hormone
  • Infertility
  • Ovarian function
  • Ovarian response
  • Unexplained infertility

Fingerprint

Dive into the research topics of 'Age-specific ovarian function'. Together they form a unique fingerprint.

Cite this