Abstract
Na+-dependent binding of 3H-Cocaine is located on dopaminergic terminals and is related to the dopamine uptake system. Studies on senescent rats indicate a decrease in 3H-Cocaine binding density in the striatum. In the same tissue an increase in the Km for dopamine uptake is observed. These changes might be relevant in the age-dependent alterations in dopaminergic function.
Original language | English |
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Pages (from-to) | 136-139 |
Number of pages | 4 |
Journal | Journals of Gerontology |
Volume | 41 |
Issue number | 2 |
DOIs | |
State | Published - 1986 |
Externally published | Yes |