Adverse Effects of Calcium Administration: Report of Two Cases

Graziano C. Carlon; William S. Howland; Paul L. Goldiner; Roberta C. Kahn; Giancarlo Bertoni; Alan D. Turnbull

doi:10.1001/archsurg.1978.01370190104021

Adverse Effects of Calcium Administration: Report of Two Cases

Graziano C. Carlon, William S. Howland, Paul L. Goldiner, Roberta C. Kahn, Giancarlo Bertoni, Alan D. Turnbull

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Abstract

Calcium chloride, 7 mg/kg, and calcium gluconate, 20 mg/kg, were administered to patients with low or low-normal levels of serum ionized calcium. Both patients had low blood pressure and cardiac index, and did not respond to digitalis, volume expansion, and β-adrenergic stimulation with dopamine. Administration of calcium caused rapid increase of serum ionized calcium levels, decrease of serum potassium levels, and development of severe cardiac arrhythmias. Atrioventricular dissociation and further fall of cardiac index and blood pressure were common features of both cases. Administration of exogenous calcium can cause severe complications, even when theoretically indicated.

Original language	English
Pages (from-to)	882-885
Number of pages	4
Journal	Archives of Surgery
Volume	113
Issue number	7
DOIs	https://doi.org/10.1001/archsurg.1978.01370190104021
State	Published - Jul 1978
Externally published	Yes

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title = "Adverse Effects of Calcium Administration: Report of Two Cases",

abstract = "Calcium chloride, 7 mg/kg, and calcium gluconate, 20 mg/kg, were administered to patients with low or low-normal levels of serum ionized calcium. Both patients had low blood pressure and cardiac index, and did not respond to digitalis, volume expansion, and β-adrenergic stimulation with dopamine. Administration of calcium caused rapid increase of serum ionized calcium levels, decrease of serum potassium levels, and development of severe cardiac arrhythmias. Atrioventricular dissociation and further fall of cardiac index and blood pressure were common features of both cases. Administration of exogenous calcium can cause severe complications, even when theoretically indicated.",

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AU - Carlon, Graziano C.

AU - Howland, William S.

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AU - Kahn, Roberta C.

AU - Bertoni, Giancarlo

AU - Turnbull, Alan D.

PY - 1978/7

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AB - Calcium chloride, 7 mg/kg, and calcium gluconate, 20 mg/kg, were administered to patients with low or low-normal levels of serum ionized calcium. Both patients had low blood pressure and cardiac index, and did not respond to digitalis, volume expansion, and β-adrenergic stimulation with dopamine. Administration of calcium caused rapid increase of serum ionized calcium levels, decrease of serum potassium levels, and development of severe cardiac arrhythmias. Atrioventricular dissociation and further fall of cardiac index and blood pressure were common features of both cases. Administration of exogenous calcium can cause severe complications, even when theoretically indicated.

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Adverse Effects of Calcium Administration: Report of Two Cases

Abstract

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