Advancing genomics to improve health equity

Ebony B. Madden, Lucia A. Hindorff, Vence L. Bonham, Tabia Henry Akintobi, Esteban G. Burchard, Kellan E. Baker, Rene L. Begay, John D. Carpten, Nancy J. Cox, Valentina Di Francesco, Denise A. Dillard, Faith E. Fletcher, Stephanie M. Fullerton, Nanibaa’ A. Garrison, Catherine M. Hammack-Aviran, Vanessa Y. Hiratsuka, James E.K. Hildreth, Carol R. Horowitz, Chanita A. Hughes Halbert, Michael InouyeAmber Jackson, Latrice G. Landry, Rick A. Kittles, Jeff T. Leek, Nita A. Limdi, Nicole C. Lockhart, Elizabeth O. Ofili, Eliseo J. Pérez-Stable, Maya Sabatello, Loren Saulsberry, Lorjetta E. Schools, Jennifer L. Troyer, Benjamin S. Wilfond, Genevieve L. Wojcik, Judy H. Cho, Sandra S.J. Lee, Eric D. Green

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Health equity is the state in which everyone has fair and just opportunities to attain their highest level of health. The field of human genomics has fallen short in increasing health equity, largely because the diversity of the human population has been inadequately reflected among participants of genomics research. This lack of diversity leads to disparities that can have scientific and clinical consequences. Achieving health equity related to genomics will require greater effort in addressing inequities within the field. As part of the commitment of the National Human Genome Research Institute (NHGRI) to advancing health equity, it convened experts in genomics and health equity research to make recommendations and performed a review of current literature to identify the landscape of gaps and opportunities at the interface between human genomics and health equity research. This Perspective describes these findings and examines health equity within the context of human genomics and genomic medicine.

Original languageEnglish
Pages (from-to)752-757
Number of pages6
JournalNature Genetics
Volume56
Issue number5
DOIs
StatePublished - May 2024

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