Advances in various techniques for isolation and purification of sterols

Sneha Dikshit, Sakshi Bubna, Anand Gupta, Piyush Kumar

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations

Abstract

Plants consist of triterpenoids such as phytosterols (PT) (C29H50O) with steroidal nuclei, including sitosterol, stigmasterol, brassicasterol and campesterol. They are hydrophobic but soluble in alcohol and other organic solvents and are isolated from industrial waste deodorizer distillates of various edible oil industries. They exist as free PT or their ester derivatives in soybean, rice, wheat, oat, cottonseed and corn fiber, and other cereals and grains. Conventional isolation techniques such as solvent extraction, distillation, evaporative fractionation, saponification and chemical esterification are employed for isolation and purification of PT. The present article reviews the various advanced separation techniques like solvent crystallization, supercritical fluid extraction, high speed counter-current chromatography and enzymatic process as strategic methods to isolate and purify sterols.

Original languageEnglish
Pages (from-to)2393-2403
Number of pages11
JournalJournal of Food Science and Technology
Volume57
Issue number7
DOIs
StatePublished - 1 Jul 2020

Keywords

  • Chromatography
  • Counter-current chromatography
  • Crystallization
  • Phytosterols
  • Supercritical fluid extraction
  • Tocopherols

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