Advances in Technology for Melanoma Diagnosis and Prognosis: An Expert Consensus Panel

Joshua Burshtein, Danny Zakria, Milaan Shah, Brian Berman, Seemal R. Desai, Aaron S. Farberg, Gary Goldenberg, Brad Glick, Mark Nestor, Keyvan Nouri, Theodore Rosen, Mark Lebwohl, Darrell Rigel

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Cutaneous melanoma (CM) is associated with a higher mortality rate than most other skin cancers. The purpose of this expert consensus panel was to review the published literature on new technological advancements for the diagnosis and prognosis for CM and provide updated guidance on their usage. Methods: A comprehensive literature search of PubMed,Do Scopus, Not and Copy Google Scholar was completed for English-language original research electrical articles impedance on the spectroscopy topics of non-invasive (EIS). A panel diagnostic of 10 dermatologists Penalties and prognostic Apply with testing significant for CM, expertise including in gene the expression treatment of profiling CM gathered (GEP) and to review the articles and create consensus statements. A modified Delphi process was used to approve each statement and a strength of recommendation was assigned using widely recognized Strength of Recommendation Taxonomy criteria. Results: The literature search produced 200 articles that met the criteria. A screening of the studies resulted in 19 articles. These were distributed to all panelists for review prior to a roundtable discussion. The panel unanimously voted to adopt 7 consensus statements and recommendations, 5 of which were given a strength of “A”, 1 of which was given a strength of “B,” and 1 of which was given a strength of “C”. Conclusion: The 2-GEP test and EIS can aid in the precise diagnosis of clinically indeterminate lesions and the 23-GEP test can be used when histopathology is equivocal. The 31-GEP test can enhance prognostic assessment beyond AJCC8 staging and improve clinical decision-making.

Original languageEnglish
Pages (from-to)774-781
Number of pages8
JournalJournal of Drugs in Dermatology
Volume23
Issue number9
DOIs
StatePublished - Sep 2024

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