Advances in systolic heart failure

Melana Yuzefpolskaya, Catherine Weinberg, Marrick Kukin

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Heart failure due to systolic dysfunction has enormous global impact. Medical management based on an understanding of the pathophysiology of the disease as well as its neurohormonal mechanisms has greatly advanced over the past 25 years. Below is a review of recent and emerging data on epidemiology and diagnosis of heart failure due to systolic dysfunction and the current and future management techniques to ameliorate this disease. At the end, we will highlight three significant trials in the field in 2009 that will impact heart failure care: STICH, MADIT-CRT, and HeartMate II.

Original languageEnglish
Article number31
JournalF1000 Medicine Reports
Issue number1
StatePublished - 27 Apr 2010
Externally publishedYes


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