Advances in PET/CT Imaging for Breast Cancer

Dorine de Jong; Elise Desperito; Karine A. Al Feghali; Laurent Dercle; Romain David Seban; Jeeban P. Das; Hong Ma; Abin Sajan; Brian Braumuller; Conor Prendergast; Connie Liou; Aileen Deng; Tina Roa; Randy Yeh; Antoine Girard; Mary M. Salvatore; Kathleen M. Capaccione

doi:10.3390/jcm12134537

Advances in PET/CT Imaging for Breast Cancer

Dorine de Jong, Elise Desperito, Karine A. Al Feghali, Laurent Dercle, Romain David Seban, Jeeban P. Das, Hong Ma, Abin Sajan, Brian Braumuller, Conor Prendergast, Connie Liou, Aileen Deng, Tina Roa, Randy Yeh, Antoine Girard, Mary M. Salvatore, Kathleen M. Capaccione

Research output: Contribution to journal › Review article › peer-review

Abstract

One out of eight women will be affected by breast cancer during her lifetime. Imaging plays a key role in breast cancer detection and management, providing physicians with information about tumor location, heterogeneity, and dissemination. In this review, we describe the latest advances in PET/CT imaging of breast cancer, including novel applications of ¹⁸F-FDG PET/CT and the development and testing of new agents for primary and metastatic breast tumor imaging and therapy. Ultimately, these radiopharmaceuticals may guide personalized approaches to optimize treatment based on the patient’s specific tumor profile, and may become a new standard of care. In addition, they may enhance the assessment of treatment efficacy and lead to improved outcomes for patients with a breast cancer diagnosis.

Original language	English
Article number	4537
Journal	Journal of Clinical Medicine
Volume	12
Issue number	13
DOIs	https://doi.org/10.3390/jcm12134537
State	Published - Jul 2023
Externally published	Yes

Keywords

F-FDG
breast cancer
PET radiotracers
triple negative breast cancer (TNBC)

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10.3390/jcm12134537

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@article{69c6697e9fd349f097c651528dd3d928,

title = "Advances in PET/CT Imaging for Breast Cancer",

abstract = "One out of eight women will be affected by breast cancer during her lifetime. Imaging plays a key role in breast cancer detection and management, providing physicians with information about tumor location, heterogeneity, and dissemination. In this review, we describe the latest advances in PET/CT imaging of breast cancer, including novel applications of 18F-FDG PET/CT and the development and testing of new agents for primary and metastatic breast tumor imaging and therapy. Ultimately, these radiopharmaceuticals may guide personalized approaches to optimize treatment based on the patient{\textquoteright}s specific tumor profile, and may become a new standard of care. In addition, they may enhance the assessment of treatment efficacy and lead to improved outcomes for patients with a breast cancer diagnosis.",

keywords = "F-FDG, breast cancer, PET radiotracers, triple negative breast cancer (TNBC)",

author = "{de Jong}, Dorine and Elise Desperito and {Al Feghali}, {Karine A.} and Laurent Dercle and Seban, {Romain David} and Das, {Jeeban P.} and Hong Ma and Abin Sajan and Brian Braumuller and Conor Prendergast and Connie Liou and Aileen Deng and Tina Roa and Randy Yeh and Antoine Girard and Salvatore, {Mary M.} and Capaccione, {Kathleen M.}",

note = "Funding Information: Capaccione has served as an advisor for Cardinal Health. Salvatore is a speaker and consultant for Genentech and Boehringer Ingelheim, and has received grant funding from Genentech and Boehringer Ingelheim. The remaining authors have nothing to disclose. No funding was obtained for this study. Publisher Copyright: {\textcopyright} 2023 by the authors.",

year = "2023",

month = jul,

doi = "10.3390/jcm12134537",

language = "English",

volume = "12",

journal = "Journal of Clinical Medicine",

issn = "2077-0383",

publisher = "MDPI AG",

number = "13",

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TY - JOUR

T1 - Advances in PET/CT Imaging for Breast Cancer

AU - de Jong, Dorine

AU - Desperito, Elise

AU - Al Feghali, Karine A.

AU - Dercle, Laurent

AU - Seban, Romain David

AU - Das, Jeeban P.

AU - Ma, Hong

AU - Sajan, Abin

AU - Braumuller, Brian

AU - Prendergast, Conor

AU - Liou, Connie

AU - Deng, Aileen

AU - Roa, Tina

AU - Yeh, Randy

AU - Girard, Antoine

AU - Salvatore, Mary M.

AU - Capaccione, Kathleen M.

N1 - Funding Information: Capaccione has served as an advisor for Cardinal Health. Salvatore is a speaker and consultant for Genentech and Boehringer Ingelheim, and has received grant funding from Genentech and Boehringer Ingelheim. The remaining authors have nothing to disclose. No funding was obtained for this study. Publisher Copyright: © 2023 by the authors.

PY - 2023/7

Y1 - 2023/7

N2 - One out of eight women will be affected by breast cancer during her lifetime. Imaging plays a key role in breast cancer detection and management, providing physicians with information about tumor location, heterogeneity, and dissemination. In this review, we describe the latest advances in PET/CT imaging of breast cancer, including novel applications of 18F-FDG PET/CT and the development and testing of new agents for primary and metastatic breast tumor imaging and therapy. Ultimately, these radiopharmaceuticals may guide personalized approaches to optimize treatment based on the patient’s specific tumor profile, and may become a new standard of care. In addition, they may enhance the assessment of treatment efficacy and lead to improved outcomes for patients with a breast cancer diagnosis.

AB - One out of eight women will be affected by breast cancer during her lifetime. Imaging plays a key role in breast cancer detection and management, providing physicians with information about tumor location, heterogeneity, and dissemination. In this review, we describe the latest advances in PET/CT imaging of breast cancer, including novel applications of 18F-FDG PET/CT and the development and testing of new agents for primary and metastatic breast tumor imaging and therapy. Ultimately, these radiopharmaceuticals may guide personalized approaches to optimize treatment based on the patient’s specific tumor profile, and may become a new standard of care. In addition, they may enhance the assessment of treatment efficacy and lead to improved outcomes for patients with a breast cancer diagnosis.

KW - F-FDG

KW - breast cancer

KW - PET radiotracers

KW - triple negative breast cancer (TNBC)

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U2 - 10.3390/jcm12134537

DO - 10.3390/jcm12134537

M3 - Review article

AN - SCOPUS:85165075485

SN - 2077-0383

VL - 12

JO - Journal of Clinical Medicine

JF - Journal of Clinical Medicine

IS - 13

M1 - 4537

ER -

Advances in PET/CT Imaging for Breast Cancer

Abstract

Keywords

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