Advances in Imaging for Tricuspid Transcatheter Edge-to-Edge Repair: Lessons Learned and Future Perspectives

Francesca Romana Prandi, Stamatios Lerakis, Martina Belli, Federica Illuminato, Davide Margonato, Lucy Barone, Saverio Muscoli, Marcello Chiocchi, Mario Laudazi, Massimo Marchei, Marco Di Luozzo, Annapoorna Kini, Francesco Romeo, Francesco Barillà

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Severe tricuspid valve (TV) regurgitation (TR) has been associated with adverse long-term outcomes in several natural history studies, but isolated TV surgery presents high mortality and morbidity rates. Transcatheter tricuspid valve interventions (TTVI) therefore represent a promising field and may currently be considered in patients with severe secondary TR that have a prohibitive surgical risk. Tricuspid transcatheter edge-to-edge repair (T-TEER) represents one of the most frequently used TTVI options. Accurate imaging of the tricuspid valve (TV) apparatus is crucial for T-TEER preprocedural planning, in order to select the right candidates, and is also fundamental for intraprocedural guidance and post-procedural follow-up. Although transesophageal echocardiography represents the main imaging modality, we describe the utility and additional value of other imaging modalities such as cardiac CT and MRI, intracardiac echocardiography, fluoroscopy, and fusion imaging to assist T-TEER. Developments in the field of 3D printing, computational models, and artificial intelligence hold great promise in improving the assessment and management of patients with valvular heart disease.

Original languageEnglish
Article number3384
JournalJournal of Clinical Medicine
Issue number10
StatePublished - May 2023


  • cardiac CT
  • cardiac MRI
  • cardiac imaging
  • echocardiography
  • structural heart interventions
  • tricuspid edge-to-edge repair
  • tricuspid valve
  • valvular heart disease


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