TY - JOUR
T1 - Advanced imaging of cardiac Paraganglioma
T2 - A systematic review
AU - Punzo, Bruna
AU - Tramontano, Liberatore
AU - Clement, Alberto
AU - Seitun, Sara
AU - Maffei, Erica
AU - Saba, Luca
AU - Nicola De Cecco, Carlo
AU - Bossone, Eduardo
AU - Narula, Jagat
AU - Cavaliere, Carlo
AU - Cademartiri, Filippo
N1 - Publisher Copyright:
© 2024
PY - 2024/8
Y1 - 2024/8
N2 - Background and aims: Cardiac ParaGangliomas (PGLs) are rare extra-adrenal tumours that arise from chromaffin cells of the sympathetic ganglia. PGL are often diagnosed incidentally, with no symptoms or symptoms related to cardiovascular dysfunction. Methods: Cardiac Computed Tomography (CCT) and Cardiac Magnetic Resonance (CMR) can detect the correct morphology and position of the lesion and provide proper tissue characterization. Nuclear medicine imaging, with Positron Emission Tomography (PET) or Single Photon Emission Computed Tomography (SPECT) with specific radiotracers, can evaluate the functionality of the PGL and to distinguish a secreting from a non-secreting tumour. Results: In association with biochemical parameters, a multimodal imaging approach, not yet standardized, can be useful both in the diagnosis, in the monitoring and in the treatment planning. Conclusions: In this systematic review, we aim to investigate the role of diagnostic imaging, in particular CCT, CMR, PET and SPECT in diagnosis, characterization and monitoring of cardiac PGLs.
AB - Background and aims: Cardiac ParaGangliomas (PGLs) are rare extra-adrenal tumours that arise from chromaffin cells of the sympathetic ganglia. PGL are often diagnosed incidentally, with no symptoms or symptoms related to cardiovascular dysfunction. Methods: Cardiac Computed Tomography (CCT) and Cardiac Magnetic Resonance (CMR) can detect the correct morphology and position of the lesion and provide proper tissue characterization. Nuclear medicine imaging, with Positron Emission Tomography (PET) or Single Photon Emission Computed Tomography (SPECT) with specific radiotracers, can evaluate the functionality of the PGL and to distinguish a secreting from a non-secreting tumour. Results: In association with biochemical parameters, a multimodal imaging approach, not yet standardized, can be useful both in the diagnosis, in the monitoring and in the treatment planning. Conclusions: In this systematic review, we aim to investigate the role of diagnostic imaging, in particular CCT, CMR, PET and SPECT in diagnosis, characterization and monitoring of cardiac PGLs.
KW - CCT
KW - CMR
KW - Paraganglioma
UR - http://www.scopus.com/inward/record.url?scp=85197415000&partnerID=8YFLogxK
U2 - 10.1016/j.ijcha.2024.101437
DO - 10.1016/j.ijcha.2024.101437
M3 - Review article
AN - SCOPUS:85197415000
SN - 2352-9067
VL - 53
JO - IJC Heart and Vasculature
JF - IJC Heart and Vasculature
M1 - 101437
ER -