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Adjunctive Pharmacotherapy for Thrombotic Coronary Lesions

Research output: Contribution to journal › Review article › peer-review

Abstract

Patients with unstable coronary syndromes are often found to have intracoronary thrombus on angiography. Despite advancements in catheter-based treatments for coronary disease, these lesions remain challenging, as percutaneous coronary intervention of thrombus-containing lesions may be associated with worse outcomes. This article reviews the literature on adjunctive pharmacotherapy in the treatment of thrombotic coronary lesions with special focus on ST-segment elevation myocardial infarction, lesions with high thrombus burden, and saphenous vein graft intervention.

Original languageEnglish
Pages (from-to)375-387
Number of pages13
JournalInterventional Cardiology Clinics
Volume2
Issue number2
DOIs
StatePublished - Apr 2013
Externally publishedYes

Keywords

  • Glycoprotein IIb/IIIa inhibitors
  • Intracoronary thrombus
  • Percutaneous coronary intervention
  • Thrombolytic therapy

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