Adjunctive Neuroprotective Therapies for Treatment of Hypoxic-Ischemic Encephalopathy (HIE)

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Abstract

Purpose of Review: To highlight emerging adjunctive neuroprotective agents for treatment of hypoxic ischemic encephalopathy (HIE). Summary: HIE is a common cause of neonatal neurologic morbidity and mortality. Therapeutic hypothermia is a standard therapy, but neuroprotection is incomplete. There are several potential adjunctive agents that can be used to augment neuroprotection when combined with hypothermia. Recent Findings: Several recent studies have evaluated the use of adjunctive therapies that, when used in combination with therapeutic hypothermia, may improve short- and long-term outcomes.

Original languageEnglish
Pages (from-to)189-193
Number of pages5
JournalCurrent Pediatrics Reports
Volume8
Issue number4
DOIs
StatePublished - Dec 2020

Keywords

  • Cooling
  • HIE
  • Hypothermia
  • Neuroprotection
  • Seizure

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