Adhesive molecules as immunologic markers of activity of multiple sclerosis

A. Miller, G. Eninya, M. Metra, A. Platkais, R. Kukaine

Research output: Contribution to journalArticlepeer-review

Abstract

The correlations between concentrations of the adhesive circulating molecules clCAM-1 and cVCAM-1 in the peripheral blood of patients with relapses-remitting multiple sclerosis (RRMS) in different clinical phases and magnetic resonance imaging (MRI) activity are presented. The patients in clinically active phase with Gd-enhancing lesions had elevated blood levels of clCAM-1 and cVCAM-1. However, 5 patients without Gd-enhancing lesions exhibited elevated clCAM-1 and cVCAM-1 levels in active phase comparing to those in remission stage that indicate a high level of sensibility of these immunologic parameters.

Original languageEnglish
Pages (from-to)35-38
Number of pages4
JournalZhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova
Volume103
Issue number1
StatePublished - 2003
Externally publishedYes

Keywords

  • Adhesive molecules
  • Magnetic resonance imaging
  • Multiple sclerosis

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