Adhesion receptors in lymphocyte activation

Tassie L. Collins, Paul D. Kassner, Barbara E. Bierer, Steven J. Burakoff

Research output: Contribution to journalArticlepeer-review

94 Scopus citations


The past several years have seen significant progress in understanding the role of T lymphocyte coreceptors in adhesion and activation. New insights have been gained in several areas: the avidity regulation of β1 and β2 integrins and their role in signal transduction; the regulation of CD8 avidity; the role of Lck in CD4 coreceptor activity; and the novel role for CD2 adhesion in the T cell antigen response.

Original languageEnglish
Pages (from-to)385-393
Number of pages9
JournalCurrent Opinion in Immunology
Issue number3
StatePublished - Jun 1994
Externally publishedYes


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