Adenoma Prevalence and Distribution Among US Latino Subgroups Undergoing Screening Colonoscopy

Sumedha V. Chablani, Lina Jandorf, Katherine DuHamel, Kristen K. Lee, Pathu Sriphanlop, Cristina Villagra, Steven H. Itzkowitz

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Background: Colorectal cancer (CRC) is the second leading malignancy diagnosed among US Latinos. Latinos in the USA represent a heterogeneous amalgam of subgroups varying in genetic background, culture, and socioeconomic status. Little is known about the frequency of CRC precursor lesions found at screening colonoscopy among Latino subgroups. Aim: The aim was to determine the prevalence and distribution of histologically confirmed adenomas found at screening colonoscopy among average-risk, asymptomatic US Latinos according to their subgroup and socio-demographic background. Methods: Cross-sectional analysis of pathological findings resulting from screening colonoscopy among average-risk, asymptomatic US Latinos aged ≥50 in two prospective randomized controlled trials at an academic medical center. Results: Among the 561 Latinos who completed screening colonoscopy, the two largest subgroups were Puerto Ricans and Dominicans. The findings among both subgroups were: adenomas 30.6%, proximal adenomas 23.5%, advanced adenomas 12.0%, and proximal advanced adenomas 8.9%. These rates are at least as high as those found at screening colonoscopy among US whites. While Puerto Ricans were more likely than Dominicans to be born in the USA, speak English, be acculturated, have a smoking history, and be obese, there were no significant differences in adenoma rates between these subgroups. Conclusions: The prevalence of adenomas, advanced adenomas, and proximal neoplasia was high among both subgroups. These findings have implications for CRC screening and surveillance among the increasingly growing Latino population in the USA.

Original languageEnglish
Pages (from-to)1637-1646
Number of pages10
JournalDigestive Diseases and Sciences
Volume62
Issue number6
DOIs
StatePublished - 1 Jun 2017

Keywords

  • Adenoma
  • Colonoscopy
  • Colorectal cancer
  • Latinos
  • Screening

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