Acute Tubular Injury and Acute Tubular Necrosis

Jeffrey M. Turner, Steven G. Coca

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations


Acute tubular injury (ATI) is characterized by damage to the renal tubular epithelial cells from ischemic or nephrotoxic insults. There are a wide array of pathologies that can result in ATI, ranging from volume-depleted states with impaired perfusion of the kidneys to atheroembolic injury following invasive vascular interventions. Given ATI is the most common cause of acute kidney injury in hospitalized patients, it is important that clinicians are intimately familiar with this topic. In this chapter, we review the causes, clinical manifestations, and treatments for ATI.

Original languageEnglish
Title of host publicationNational Kidney Foundation's Primer on Kidney Diseases
Number of pages9
ISBN (Electronic)9780323477949
ISBN (Print)9780323510608
StatePublished - 1 Jan 2017


  • acute kidney injury
  • acute tubular injury
  • acute tubular necrosis
  • cholesterol atheroembolic kidney disease
  • heme pigment nephropathy
  • hemoglobinuria
  • ischemic kidney injury
  • kidney infarction
  • rhabdomyolysis
  • tumor lysis syndrome


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