Acute HCV in HIV-Infected MSM: Modes of Acquisition, Liver Fibrosis, and Treatment

Emma Kaplan-Lewis; Daniel Seth Fierer

doi:10.1007/s11904-015-0279-3

Acute HCV in HIV-Infected MSM: Modes of Acquisition, Liver Fibrosis, and Treatment

Emma Kaplan-Lewis, Daniel Seth Fierer

Research output: Contribution to journal › Review article › peer-review

32 Scopus citations

Abstract

Hepatitis C virus (HCV) is not considered to be efficiently transmitted sexually, but since the early 2000s, HCV infection of HIV-infected men who have sex with men has emerged as an epidemic worldwide. In this review, we discuss the epidemiology of sexually transmitted acute HCV, the growing body of literature regarding risk factors for acquisition, and possible mechanisms of transmission. We also discuss the progression of liver disease in these men and the advances in therapy of acute HCV with interferon-free regimens and put forth our current approach of evaluating and treating these men in New York City.

Original language	English
Pages (from-to)	317-325
Number of pages	9
Journal	Current HIV/AIDS Reports
Volume	12
Issue number	3
DOIs	https://doi.org/10.1007/s11904-015-0279-3
State	Published - 10 Sep 2015

Keywords

Acute hepatitis C (HCV) infection
Direct-acting antivirals (DAA)
HIV/AIDS
Liver fibrosis
Men who have sex with men (MSM)
Sexual transmission

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10.1007/s11904-015-0279-3

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title = "Acute HCV in HIV-Infected MSM: Modes of Acquisition, Liver Fibrosis, and Treatment",

abstract = "Hepatitis C virus (HCV) is not considered to be efficiently transmitted sexually, but since the early 2000s, HCV infection of HIV-infected men who have sex with men has emerged as an epidemic worldwide. In this review, we discuss the epidemiology of sexually transmitted acute HCV, the growing body of literature regarding risk factors for acquisition, and possible mechanisms of transmission. We also discuss the progression of liver disease in these men and the advances in therapy of acute HCV with interferon-free regimens and put forth our current approach of evaluating and treating these men in New York City.",

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AU - Fierer, Daniel Seth

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Y1 - 2015/9/10

N2 - Hepatitis C virus (HCV) is not considered to be efficiently transmitted sexually, but since the early 2000s, HCV infection of HIV-infected men who have sex with men has emerged as an epidemic worldwide. In this review, we discuss the epidemiology of sexually transmitted acute HCV, the growing body of literature regarding risk factors for acquisition, and possible mechanisms of transmission. We also discuss the progression of liver disease in these men and the advances in therapy of acute HCV with interferon-free regimens and put forth our current approach of evaluating and treating these men in New York City.

AB - Hepatitis C virus (HCV) is not considered to be efficiently transmitted sexually, but since the early 2000s, HCV infection of HIV-infected men who have sex with men has emerged as an epidemic worldwide. In this review, we discuss the epidemiology of sexually transmitted acute HCV, the growing body of literature regarding risk factors for acquisition, and possible mechanisms of transmission. We also discuss the progression of liver disease in these men and the advances in therapy of acute HCV with interferon-free regimens and put forth our current approach of evaluating and treating these men in New York City.

KW - Acute hepatitis C (HCV) infection

KW - Direct-acting antivirals (DAA)

KW - HIV/AIDS

KW - Liver fibrosis

KW - Men who have sex with men (MSM)

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JF - Current HIV/AIDS Reports

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Acute HCV in HIV-Infected MSM: Modes of Acquisition, Liver Fibrosis, and Treatment

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