Acute Glucose Response Properties Beyond Feeding

C. Joseph Burnett; Michael J. Krashes

doi:10.1016/j.molmed.2016.03.001

Acute Glucose Response Properties Beyond Feeding

C. Joseph Burnett, Michael J. Krashes

Research output: Contribution to journal › Short survey › peer-review

Abstract

Hypothalamic AgRP neurons potently coordinate feeding behavior to ensure an organism's viability. However, their acute role in glucose-regulatory function remains to be addressed. Steculorum et al. now report that activation of a specific set of AgRP neurons results in an impairment of insulin-stimulated glucose uptake in brown fat through a myogenic signature program.

Original language	English
Pages (from-to)	356-358
Number of pages	3
Journal	Trends in Molecular Medicine
Volume	22
Issue number	5
DOIs	https://doi.org/10.1016/j.molmed.2016.03.001
State	Published - 1 May 2016
Externally published	Yes

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title = "Acute Glucose Response Properties Beyond Feeding",

abstract = "Hypothalamic AgRP neurons potently coordinate feeding behavior to ensure an organism's viability. However, their acute role in glucose-regulatory function remains to be addressed. Steculorum et al. now report that activation of a specific set of AgRP neurons results in an impairment of insulin-stimulated glucose uptake in brown fat through a myogenic signature program.",

author = "Burnett, {C. Joseph} and Krashes, {Michael J.}",

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AU - Burnett, C. Joseph

AU - Krashes, Michael J.

PY - 2016/5/1

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N2 - Hypothalamic AgRP neurons potently coordinate feeding behavior to ensure an organism's viability. However, their acute role in glucose-regulatory function remains to be addressed. Steculorum et al. now report that activation of a specific set of AgRP neurons results in an impairment of insulin-stimulated glucose uptake in brown fat through a myogenic signature program.

AB - Hypothalamic AgRP neurons potently coordinate feeding behavior to ensure an organism's viability. However, their acute role in glucose-regulatory function remains to be addressed. Steculorum et al. now report that activation of a specific set of AgRP neurons results in an impairment of insulin-stimulated glucose uptake in brown fat through a myogenic signature program.

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U2 - 10.1016/j.molmed.2016.03.001

DO - 10.1016/j.molmed.2016.03.001

M3 - Short survey

C2 - 27052261

AN - SCOPUS:84961882189

SN - 1471-4914

VL - 22

SP - 356

EP - 358

JO - Trends in Molecular Medicine

JF - Trends in Molecular Medicine

IS - 5

ER -

Acute Glucose Response Properties Beyond Feeding

Abstract

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