TY - JOUR
T1 - Acitretin in combination with UVB or PUVA
AU - Lebwohl, M.
PY - 1999
Y1 - 1999
N2 - Combination therapy of psoriasis with acitretin and phototherapy (psoralen-ultraviolet A [PUVA] or ultraviolet B [UVB]) offers multiple advantages over use of either modality alone. As monotherapy, acitretin in doses of 50 mg/day is moderately effective, but is associated with numerous side effects. Single modality treatment with UVB or PUVA involves multiple visits over a period of months and is also associated with dose-limiting side effects. When used in combination, lower doses of both modalities can be used more effectively, helping to reduce side effects. In addition, clearing occurs much more quickly, reducing treatment time and number of phototherapy visits. Moreover, patients whose psoriasis does not clear with monotherapy will often achieve significant clearing with the combination of acitretin and phototherapy.
AB - Combination therapy of psoriasis with acitretin and phototherapy (psoralen-ultraviolet A [PUVA] or ultraviolet B [UVB]) offers multiple advantages over use of either modality alone. As monotherapy, acitretin in doses of 50 mg/day is moderately effective, but is associated with numerous side effects. Single modality treatment with UVB or PUVA involves multiple visits over a period of months and is also associated with dose-limiting side effects. When used in combination, lower doses of both modalities can be used more effectively, helping to reduce side effects. In addition, clearing occurs much more quickly, reducing treatment time and number of phototherapy visits. Moreover, patients whose psoriasis does not clear with monotherapy will often achieve significant clearing with the combination of acitretin and phototherapy.
UR - http://www.scopus.com/inward/record.url?scp=0032832339&partnerID=8YFLogxK
U2 - 10.1016/S0190-9622(99)70362-2
DO - 10.1016/S0190-9622(99)70362-2
M3 - Article
C2 - 10459143
AN - SCOPUS:0032832339
SN - 0190-9622
VL - 41
SP - S22-S24
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 3 SUPPL.
ER -