Acetylcholine Receptor Stimulation for Cognitive Enhancement: Better the Devil You Know?

Mark G. Baxter, Johanna L. Crimins

Research output: Contribution to journalShort surveypeer-review

12 Scopus citations

Abstract

Drug treatments to improve memory focus on enhancing acetylcholine. However, Vijayraghavan and colleagues (2018) show that direct stimulation of the M1 muscarinic acetylcholine receptor adversely affected neuronal activity in prefrontal cortex related to working memory for behavioral rules. Drug treatments to improve memory focus on enhancing acetylcholine. However, Vijayraghavan and colleagues (2018) show that direct stimulation of the M1 muscarinic acetylcholine receptor adversely affected neuronal activity in prefrontal cortex related to working memory for behavioral rules.

Original languageEnglish
Pages (from-to)1064-1066
Number of pages3
JournalNeuron
Volume98
Issue number6
DOIs
StatePublished - 27 Jun 2018

Keywords

  • Alzheimer's disease
  • cholinergic
  • dementia

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