Acetylcholine noise: Analysis after chemical modification of receptor

E. M. Landau, D. Ben-Haim

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

The elementary voltage pulses ("shot effects") produced by the action of acetylcholine molecules on the receptor were studied by analyzing the membrane voltage fluctuations ("noise") after acetylcholine application at the frog neuromuscular junction. The amplitude of these pulses was decreased after treatment with a disulfide-bond reducing agent. The shot effect may thus depend on the structure or conformation of the receptor molecule.

Original languageEnglish
Pages (from-to)944-946
Number of pages3
JournalScience
Volume185
Issue number4155
DOIs
StatePublished - 1974
Externally publishedYes

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