Acetylcholine for male LUTS

Steven J. Weissbart, Bilal Chughtai, Dean Elterman, Richard Lee, Alexis Te, Steven Kaplan

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

In this review, we present the evidence on the safety and efficacy of anticholinergic therapy for men with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) and emphasize the data published over the past year. This review discusses two classes of medications whose mechanism of action attenuates the effect of acetylcholine on the LUT: anticholinergics and botulinum toxin. We review the randomized controlled trials that investigate the efficacy and side effects of anticholinergics when used in men with LUTS secondary to BPH. We emphasize new studies and developments that have been made in the past year.

Original languageEnglish
Pages (from-to)413-419
Number of pages7
JournalCurrent Urology Reports
Volume13
Issue number6
DOIs
StatePublished - Dec 2012
Externally publishedYes

Keywords

  • Acetylcholine
  • Anticholinergic therapy
  • Benign prostatic hyperplasia
  • Botulinum toxin
  • Lower urinary tracts symptoms
  • Overactive bladder

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