Acetate intolerance during hemodialysis

A. Novello; R. C. Kelsch; R. E. Easterling

Acetate intolerance during hemodialysis

A. Novello
, R. C. Kelsch
, R. E. Easterling

Research output: Contribution to journal › Article › peer-review

96 Scopus citations

Abstract

Acetate is frequently substituted for bicarbonate in hemodialysis solutions. Plasma acetate and bicarbonate concentrations were measured in nine patients with chronic renal failure undergoing hemodialysis with dialyzate containing acetate. In three patients (2 children and 1 adult) plasma acetate concentrations exceeded 15 mEq/liter during the dialysis. The mechanisms leading to acetate intolerance are probably multiple. It cannot be assumed that dialysis with acetate containing solutions will restore the buffer anion deficit characteristic of chronic renal failure.

Original language	English
Pages (from-to)	29-32
Number of pages	4
Journal	Clinical Nephrology
Volume	5
Issue number	1
State	Published - 1976
Externally published	Yes

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title = "Acetate intolerance during hemodialysis",

abstract = "Acetate is frequently substituted for bicarbonate in hemodialysis solutions. Plasma acetate and bicarbonate concentrations were measured in nine patients with chronic renal failure undergoing hemodialysis with dialyzate containing acetate. In three patients (2 children and 1 adult) plasma acetate concentrations exceeded 15 mEq/liter during the dialysis. The mechanisms leading to acetate intolerance are probably multiple. It cannot be assumed that dialysis with acetate containing solutions will restore the buffer anion deficit characteristic of chronic renal failure.",

author = "A. Novello and Kelsch, \{R. C.\} and Easterling, \{R. E.\}",

year = "1976",

language = "English",

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journal = "Clinical Nephrology",

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T1 - Acetate intolerance during hemodialysis

AU - Novello, A.

AU - Kelsch, R. C.

AU - Easterling, R. E.

PY - 1976

Y1 - 1976

N2 - Acetate is frequently substituted for bicarbonate in hemodialysis solutions. Plasma acetate and bicarbonate concentrations were measured in nine patients with chronic renal failure undergoing hemodialysis with dialyzate containing acetate. In three patients (2 children and 1 adult) plasma acetate concentrations exceeded 15 mEq/liter during the dialysis. The mechanisms leading to acetate intolerance are probably multiple. It cannot be assumed that dialysis with acetate containing solutions will restore the buffer anion deficit characteristic of chronic renal failure.

AB - Acetate is frequently substituted for bicarbonate in hemodialysis solutions. Plasma acetate and bicarbonate concentrations were measured in nine patients with chronic renal failure undergoing hemodialysis with dialyzate containing acetate. In three patients (2 children and 1 adult) plasma acetate concentrations exceeded 15 mEq/liter during the dialysis. The mechanisms leading to acetate intolerance are probably multiple. It cannot be assumed that dialysis with acetate containing solutions will restore the buffer anion deficit characteristic of chronic renal failure.

UR - https://www.scopus.com/pages/publications/0017232131

M3 - Article

C2 - 2405

AN - SCOPUS:0017232131

SN - 0301-0430

VL - 5

SP - 29

EP - 32

JO - Clinical Nephrology

JF - Clinical Nephrology

IS - 1

ER -

Acetate intolerance during hemodialysis

Abstract

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